HIV and ID Observations

October 8th, 2008

The French Win This One

The 2008 Nobel Prize in Medicine goes to Françoise Barré-Sinoussi and Luc Montagnier for discovery of HIV.  They each get one-quarter of the prize money, with one-half going to Harald zur Hausen for showing the relationship between human papillomavirus and cervical cancer. For the record, if you search the Nobel press release for the word “Gallo”, […]

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October 1st, 2008

Deadlines of Note

Just a reminder of some interesting deadlines/events out there, in case you were too wrapped up sharpening pencils for tomorrow’s Vice Presidential debate: As of today, Medicare will no longer reimburse hospitals for medical errors — which includes some hospital-acquired infections.  According to this article, several other payors (including private insurers) are using this as a precedent […]

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September 29th, 2008

Required Reading: The Value of ID Specialists

In the most recent issue of Clinical Infectious Diseases, there’s a comprehensive review of the value of an ID specialist from the perspective of non-patient care activities.  Covered in particular are: Antibiotic stewardship Infection control Monitoring rates of nosocomial infections Managing health care worker “well-being and exposures” Also included are tables listing dozens of studies quantifying the value […]

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September 18th, 2008

C. diff: The cure for antibiotic abuse

Even with market doom-and-gloom dominating the news, there’s a good article in yesterday’s Wall Street Journal on Clostridium difficile (C. diff).  It gives an accurate summary (in lay language) of the problem, several pertinent clinical anecdotes, and quotations from national experts. But this part in particular caught my eye: She says that among other measures, the hospital has […]

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September 10th, 2008

Yes, TNF blockers increase infection risk. Now what?

So the FDA has issued (another) warning about TNF (tumor necrosis factor) blockers and increased infection risk, this time focusing on fungal infections, in particular histoplasmosis.  TNF blockers are used for treatment of rheumatoid arthritis, Crohn’s Disease, ankylosing spondylitis, psoriasis, and a wide range of other autoimmune diseases, both in approved and in off-label use. ID/HIV specialists […]

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September 5th, 2008

West Nile Virus and Friday Night Lights

The town of Braintree, just south of Boston, has cancelled Friday night high school football games until the first frost of the year due to concerns about West Nile.  Apparently the campus has a lake and wetlands,  good breeding grounds for mosquitoes.  “This is all in the name of safety,” says the school headmaster. (If someone […]

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August 22nd, 2008

We have met the enemy … and it is MRSA

In Jerry Groopman’s recent New Yorker piece on antibiotic-resistant bacteria, he quotes Dr. Louis Rice from the Cleveland VA, who uses the term “ESKAPE” bacteria:  an acronym for Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumanni, Pseudomonas aeruginosa, and Enterobacter. Nothing against the mostly gram-negative nasties in this list (and the focus of the New Yorker article), […]

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August 8th, 2008

More from Mexico City

A bit more travelogue from the XVII International AIDS Conference: It’s impossible to see everything you want at such a large, sprawling conference, sometimes because of conflicting meetings, sometimes because the room is full, sometimes because of a feeling analagous to being in a giant museum for too many hours — fatigue just takes over.  But I’m […]

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August 4th, 2008

Mexico City: Drive on the right … most of the time

Some early and completely non-scientific observations from the XVII AIDS Conference, taking place now in Mexico City: Everyone said getting to and from the Banamex Convention Center would be difficult, and of course they were right.  Mexico City is the largest city in the Western Hemisphere, has a road/traffic system that makes driving in Boston seem downright […]

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July 29th, 2008

Antiretroviral Rounds: Immediate ART After an OI — Are We There Yet?

A few things have been guaranteed to get widely divergent views among HIV specialists — and one of them was when to start antiretroviral therapy in someone presenting with an acute OI.  However, in the latest Antiretroviral Rounds, our two experts (Raphy Landovitz and Phil Grant/Andrew Zolopa) kind of agreed.  They’d start immediately.    At least that’s […]

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