Articles matching the ‘Infectious Diseases’ Category

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June 7th, 2020

Hydroxychloroquine Not Effective in Preventing COVID-19 — In Praise of a Negative Clinical Trial

The headlines might read, Malaria Drug Ineffective in Preventing COVID-19 — but that doesn’t do justice to a remarkable clinical trial, just published this week in the New England Journal of Medicine. Led by Dr. David Boulware at the University of Minnesota, the study asked this question:  Does hydroxychloroquine (HCQ) prevent the development of COVID-19 in people […]


May 31st, 2020

America the Not So Beautiful Right Now, with a Must-Read Book Suggestion

Have you read W. Kamau Bell’s The Awkward Thoughts of W. Kamau Bell:  Tales of a 6′ 4″, African American, Heterosexual, Cisgender, Left-Leaning, Asthmatic, Black and Proud Blerd, Mama’s Boy, Dad, and Stand-Up Comedian? If you haven’t, may I suggest you put it at the top of your list, and pronto? In addition to being funny, […]


May 25th, 2020

A Major Advance in Non-COVID-19 ID Research You Might Have Missed

One thing about the COVID-19 pandemic — other important non-COVID ID news gets crowded out. As a prime example, take HPTN 083, a major clinical trial in HIV prevention. The results are a big deal, and should have garnered more attention when they were released last week. This randomized, double-blind pre-exposure prophylaxis (PrEP) study compared long-acting injectable […]


May 10th, 2020

Thank You to Inpatient Nurses — The People Doing the Most Direct COVID-19 Patient Care

Anyone who does inpatient medicine or surgery knows well the major imbalance in time spent on direct patient care between doctors and nurses. Nurses spend way more time actually with patients than we do — I’m referring to time in the rooms caring for patients. While we round and review charts, document lab test results, bring up […]


May 6th, 2020

Early Memories of Burton “Bud” Rose, Founder of UpToDate — and Medical Education Visionary

Let’s rewind the clock a bit — OK, a lot. Ancient history. It’s winter, 1986. An interview day for medical residency at Brigham and Women’s Hospital. A bunch of us nervous medical students sit in a conference room, wearing our interview suits, while Dr. Marshall Wolf tells us what to expect that day. Amazingly, Marshall knows all […]


April 27th, 2020

Leaked Remdesivir Study Information, Tocilizumab and Sarilumab Trials, and the Hazards of Early COVID-19 Research Findings

In the podcast I did with Helen Branswell — Infectious Diseases and global health reporter for STAT — she mentioned that the flow of scientific information for the COVID-19 pandemic made the commonly cited “drinking from a fire hose” analogy somehow inadequate. Since she’s from Canada, I offered Niagara Falls as an alternative, to which she […]


April 19th, 2020

Gratitude Before, During, and After Rounding on COVID-19 Service

It snowed in Boston yesterday morning — heavy, wet flakes covered the daffodils and tulips that just started coming up — but this brief return to winter didn’t make my red, itchy eyes from spring pollen feel any better. The flowers didn’t look too happy either. Oh well. But just as the annual misery of a typical […]


April 12th, 2020

IDSA’s COVID-19 Treatment Guidelines Highlight Difficulty of “Don’t Just Do Something, Stand There”

The Infectious Diseases Society of America (IDSA) gathered a series of experts for what were undoubtedly many late-night calls, reviews of published and pre-print literature, and revisions (of revisions), and admirably generated a set of treatment guidelines for COVID-19. The problem — there is no proven effective treatment for COVID-19. That is, there’s no proven treatment based […]


April 6th, 2020

Dear Nation — A Series of Apologies on COVID-19

(What I’m sincerely hoping we’ll be hearing in an upcoming press conference, and soon.) Dear Fellow Americans, I’d like to take a brief moment in today’s press briefing to say something that is long overdue. I’m sorry. In a moment, I’ll cite the specifics of what I’ll be apologizing about. But first, I want to acknowledge the sadness of this […]


March 26th, 2020

No Opening Day … Yet

My memories of spring have always included baseball. I worshiped my older brother Ben — he’s still pretty great — and he loved baseball. So as the days in March shifted from cold and dark to slightly less cold and much less dark, the game he played so brilliantly with his friends pulled me in. I […]


HIV Information: Author Paul Sax, M.D.

Paul E. Sax, MD

Contributing Editor

NEJM Journal Watch
Infectious Diseases

Biography | Disclosures | Summaries

Learn more about HIV and ID Observations.