Posts Tagged ‘COVID-19’


July 26th, 2020

Time to Amplify Our Voices Calling for Inexpensive Rapid Home Testing for COVID-19

Earlier this month, I highlighted how inexpensive rapid home testing for COVID-19 could get us out of this mess faster than a vaccine. To spare you re-reading the whole thing, here are the main points. Imagine a simple test done on a saliva sample placed on a paper strip. Results back in 15 minutes. Available without a […]

July 19th, 2020

Reaching Out to ID Doctors in COVID-19 Hot Spots — You Must Be Truly Exhausted

For us ID doctors in most of the northeastern United States (and Chicago and Detroit and some other northern cities), March and April hit us like a giant wave of never-ending calls, pages, emails, and crises. With COVID-19 case numbers increasing every day, the challenges crashed down on us in an endless torrent of hospital needs […]

July 5th, 2020

Rapid, Inexpensive Home Testing for COVID-19 May Get Us Out of This Mess Before a Vaccine

As cases of COVID-19 continue to climb to record numbers, it might seem impossible that something is already out there that could dramatically reduce new infections — and even bring us back to some semblance of normal life. I’m not referring to a vaccine. It’s a rapid, inexpensive home test. You’re forgiven for being incredulous. Indeed, you […]

June 28th, 2020

Is COVID-19 Different in People with HIV?

From the start of the COVID-19 pandemic, one of most common questions I’ve received has been whether COVID-19 has different clinical manifestations in people with HIV. Would it be more lethal since people with HIV have impaired immune systems? Or milder since some of the damage in severe cases is immunologically mediated? Or would it be similar, […]

June 7th, 2020

Hydroxychloroquine Not Effective in Preventing COVID-19 — In Praise of a Negative Clinical Trial

The headlines might read, Malaria Drug Ineffective in Preventing COVID-19 — but that doesn’t do justice to a remarkable clinical trial, just published this week in the New England Journal of Medicine. Led by Dr. David Boulware at the University of Minnesota, the study asked this question:  Does hydroxychloroquine (HCQ) prevent the development of COVID-19 in people […]

April 27th, 2020

Leaked Remdesivir Study Information, Tocilizumab and Sarilumab Trials, and the Hazards of Early COVID-19 Research Findings

In the podcast I did with Helen Branswell — Infectious Diseases and global health reporter for STAT — she mentioned that the flow of scientific information for the COVID-19 pandemic made the commonly cited “drinking from a fire hose” analogy somehow inadequate. Since she’s from Canada, I offered Niagara Falls as an alternative, to which she […]

April 19th, 2020

Gratitude Before, During, and After Rounding on COVID-19 Service

It snowed in Boston yesterday morning — heavy, wet flakes covered the daffodils and tulips that just started coming up — but this brief return to winter didn’t make my red, itchy eyes from spring pollen feel any better. The flowers didn’t look too happy either. Oh well. But just as the annual misery of a typical […]

April 12th, 2020

IDSA’s COVID-19 Treatment Guidelines Highlight Difficulty of “Don’t Just Do Something, Stand There”

The Infectious Diseases Society of America (IDSA) gathered a series of experts for what were undoubtedly many late-night calls, reviews of published and pre-print literature, and revisions (of revisions), and admirably generated a set of treatment guidelines for COVID-19. The problem — there is no proven effective treatment for COVID-19. That is, there’s no proven treatment based […]

April 6th, 2020

Dear Nation — A Series of Apologies on COVID-19

(What I’m sincerely hoping we’ll be hearing in an upcoming press conference, and soon.) Dear Fellow Americans, I’d like to take a brief moment in today’s press briefing to say something that is long overdue. I’m sorry. In a moment, I’ll cite the specifics of what I’ll be apologizing about. But first, I want to acknowledge the sadness of this […]

March 26th, 2020

No Opening Day … Yet

My memories of spring have always included baseball. I worshiped my older brother Ben — he’s still pretty great — and he loved baseball. So as the days in March shifted from cold and dark to slightly less cold and much less dark, the game he played so brilliantly with his friends pulled me in. I […]

HIV Information: Author Paul Sax, M.D.

Paul E. Sax, MD

Contributing Editor

NEJM Journal Watch
Infectious Diseases

Biography | Disclosures | Summaries

Learn more about HIV and ID Observations.