HIV and ID Observations

December 6th, 2010

Tough Diagnoses: Neurosyphilis, Then and Now

During Thanksgiving, my brother-in-law — who is a professional musician and also a passionate history buff — gave me a scholarly paper to review on the strange death of the famous American explorer Meriwether Lewis, of “Lewis and Clark” fame. The bottom line?  Lewis may well have had neurosyphilis — at least that’s the premise of […]

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November 23rd, 2010

iPrEx: First-Ever PrEP Efficacy Study Published

It’s been quite the year (plus a month) for HIV prevention research. That glimmer of hope from the Thai vaccine trial.  The striking effect of HIV-treatment as prevention.  The positive results of the CAPRISA vaginal microbicide study, which were presented to rapturous applause this summer in Vienna. And today, the iPrEx study is published, which shows that […]

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November 17th, 2010

Ferlater Antibiotics

In this absolutely hysterical, laugh-out-loud comedy routine, Mal Z. Lawrence describes a woman at a Catskill hotel, piling danish into her handbag. She calls them “ferlater danish” — as opposed to the ones she’s eating at breakfast, those are “fernow.” Did you ever have one of your patients request “ferlater” antibiotics?  That is, ask that […]

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November 12th, 2010

Tesamorelin is Approved

This just in from the FDA: The U.S. Food and Drug Administration today approved Egrifta (tesamorelin) to treat HIV patients with lipodystrophy, a condition in which excess fat develops in different areas of the body, most notably around the liver, stomach, and other abdominal organs. The condition is associated with many antiretroviral drugs used to […]

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November 7th, 2010

Welcome to the Click-Fest

Let me start by confessing I’m something of a gadget freak.  I was an early Palm Pilot adoptor, loved the iPod from the get-go, and need to avoid CNET, Engadget, Gizmodo, and David Pogue’s columns for the New York Times when deadlines loom. Not surprisingly, I embraced the shift to electronic medical records (EMRs) enthusiastically. […]

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November 4th, 2010

XMRV and CFS: More Yay and Nay

Does XMRV cause Chronic Fatigue Syndrome?  Or more accurately, is it even associated with CFS? I’ve been putting off writing about this for a while, as I knew colleagues of mine had a paper in press on the topic, and I wanted the dust to settle a bit more on the controversy. But of course […]

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October 7th, 2010

Post-Halladay Video Treat: Prospects for HIV Cure

For a little entertainment between playoff games — but how could anyone beat the guy in the picture? — you might want to check out this interview I did with Dan Kuritzkes about the prospects for an HIV cure. So which do you think we’ll see first — an HIV cure or a vaccine?  And I don’t mean […]

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September 27th, 2010

CROI 2011: February 27-March 2, Boston

Yes, I know it’s already listed on the official web site. But since it’s in Boston, and since this post drove tons of internet traffic this way, why not cite it again? And let’s all hope that February here in 2011 is nothing like February 1978.  Nah, that couldn’t happen …

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September 17th, 2010

What Are These Conferences?

With ICAAC now completed — which took place in a city called Boston but seemed far, far, from home (see picture) — it seems timely to inquire about another form of “scientific” conference. Every so often, I’ll receive an email like this (slightly edited to protect the sender, whomever he or she may be): Dear […]

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August 26th, 2010

Lyme Cases Up — Anecdotes, True Epidemiology, and More Anecdotes

All of us New England-based ID doctors (and internists and family practitioners and pediatricians and NPs/PAs in primary care) who have been in practice a while will tell you that Lyme cases have been increasing for years. And it’s not just the number of cases, it’s also where and when they are occurring.  A few years […]

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