An ongoing dialogue on HIV/AIDS, infectious diseases,
October 17th, 2012
It’s Time to Tell Our Patients to Stop Their Vitamin Supplements
Over in JAMA, there’s a large study out today that (yet again) failed to demonstrate a benefit of vitamins. Over 3000 patients with HIV in Tanzania were randomized to receive either high-dose or standard-dose multivitamin supplementation, in addition to “HAART” (ugh). Though the study was planned for 24 months, it was stopped early by the Data Safety […]
October 15th, 2012
ID Doctors are Clueless about Treating Helicobacter
Every so often, we’ll get a referral from a gastroenterologist about a refractory case of Helicobacter pylori. Usually the patient has been treated multiple times, and still has symptoms and a positive test. Naturally a referral to a specialist in Infectious Diseases seems warranted. But the reality is that this is like the IV nurse contacting the […]
October 11th, 2012
Back to School: Questions at the “ID in Primary Care” Course
We do a post-graduate course each year called “ID in Primary Care,” and it’s a great way for us to find out what people in outpatient primary care practice are thinking about from the ID perspective. I told the participants this year I’d post some of their most interesting questions on this site, with the hope that […]
October 8th, 2012
With One Month To Go, Candidates Eke Out Votes Wherever They Can
From the Department of Opportunistic Expediency, we have this brazen pitch from one of our two presidential hopefuls: Romney and Ryan will do more to fight the spread of Lyme Disease … As president, Mitt Romney will ensure that real action is taken to get control of this epidemic that is wreaking havoc on Northern Virginia. Suffice […]
October 2nd, 2012
The Drug-Resistant Gonorrhea: How Much of a Threat?
By now, all ID docs know about the ceftriaxone-resistant Neisseria gonorrhoeae. Or, more accurately, we’ve read about it, since the vast majority of gonorrhea cases are treated in emergency rooms, STI clinics, college health facilities, and various primary care settings — not places that most ID doctors typically work. Plus, hardly anyone does susceptibility testing or […]
September 24th, 2012
Quick Question: An Etiquette Column for ID Specialists
(First in what will undoubtedly be a recurring series.) Hi Paul: What do you do when someone in a non-medical setting gets something really wrong, and it’s in our field? Here’s why I’m asking: I was picking up my 9-year-old son from school the other day, and his teacher reported to me that they were worried […]
September 19th, 2012
It’s Time to Dump the HIV Western Blot
Hard to believe, but we have to get rid of the HIV Western blot — at least as our HIV confirmatory test. Here’s why (case adapted from several seen the past few years; I’m sure most of you have seen similar): 30-year-old man, high risk for HIV. He’s worried he might have become infected due to recent […]
September 11th, 2012
Are Fluoroquinolones Really More Dangerous Than Other Antibiotics?
In today’s New York Times, health writer Jane Brody slams quinolone antibiotics: Part of the problem is that fluoroquinolones are often inappropriately prescribed. Instead of being reserved for use against serious, perhaps life-threatening bacterial infections like hospital-acquired pneumonia, these antibiotics are frequently prescribed for sinusitis, bronchitis, earaches and other ailments that may resolve on their own or can be […]
September 8th, 2012
People Fear EEE and West Nile, but not Influenza — Can Someone Explain Why?
OK, here’s a quick quiz — match the viral infection with the average annual US deaths: 1. Eastern Equine Encephalitis A. 36,000, mostly in the elderly 2. Influenza B. < 10, mostly in the elderly I know, it was an easy one — 1 goes with B, and 2 with A. Here’s a good reference for more on […]
August 31st, 2012
“PEARLS” Study a Massive, Impressive Accomplishment
One of the most frequent criticisms of randomized clinical trials of HIV therapy is that certain patient groups — in particular gay men — are over represented compared to the HIV population as a whole. For example, in the recently published and presented clinical trials of the Quad and dolutegravir, women accounted for < 20% of […]