HIV and ID Observations

April 16th, 2017

Mark Wainberg and the Enduring Importance of 3TC

Last week, the HIV/ID research world lost one of its leaders and pioneers when Dr. Mark Wainberg unexpectedly died. An astute, thoughtful virologist — and a warm, engaging person — he led the HIV research program at McGill University in Montreal for years, contributing to the field both through his research and patient advocacy. A strong voice […]

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April 5th, 2017

Here’s What Happens When You Search “Infectious Diseases” on a Stock Photo Site

Everyone knows a stock image when they see one. The people don’t look real, the activities are staged, and everything has an air-brushed, frozen quality that screams, “This is not a real thing, but we need some copyright-free graphics and this is the best we can do.” Strangely depersonalized group photos, animals in human activities, and computer-created illustrations just […]

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March 25th, 2017

HIV and Hepatitis C Are No Longer the Most Serious Infectious Threats to People Who Inject Drugs

I had dinner with my daughter Mimi the other evening, and was ruminating about how things have changed since I started work as an Infectious Diseases doctor around 25 years ago. Here’s an excerpt of our chat: Me:  There are way more cases of endocarditis in young people than there used to be, a complication of injecting drugs. People in their 20s and […]

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March 19th, 2017

What Health and Human Services Secretary Tom Price Should Be Saying About Required Immunizations

In case you missed it, Secretary of Health and Human Services Tom Price said this past week that the states should make decisions about mandatory vaccination policies. Here’s the actual clip: HHS Secretary Tom Price says it should be up to states to regulate whether immunizations are required https://t.co/soyH0YpO5E — CNN Politics (@CNNPolitics) March 16, 2017 What’s notable here isn’t the […]

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March 14th, 2017

Poll: Should We Allow 24-Hour Shifts Again For Interns?

Over on Boston’s NPR site, I wrote a piece about the decision by the Accreditation Council for Graduate Medical Education (ACGME) to allow 24 hour (or longer) work shifts again for interns. My goal in writing the piece was to relay what I experienced doing these long shifts way back when during my internship — the good […]

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March 5th, 2017

High-Dose Flu Vaccine, Robert De Niro Challenge, Antibiotics for Colds, and More: March Comes in Like a Lion ID Link-o-Rama

Here are a few ID/HIV items blowing around the neighborhood on this, a bitterly cold and windy first weekend of March (at least here in Boston): Compared with the standard dose vaccine, the high-dose flu vaccine reduced deaths among older adults. The benefit was seen in the 2012-13 flu season, but not 2013-14. The authors speculate that the circulating […]

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February 26th, 2017

Improving Outcomes with ID Consultation: Three More Papers For the Collection

Several years ago, one of my very brilliant colleagues posed an interesting question. Why do ID specialists even exist? “After all,” he said in an accent that happens to be a distinctive mix of several former British colonies. “There is nothing we do that other doctors couldn’t also do, provided they had the motivation.” He had a point — with no required […]

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February 19th, 2017

Really Rapid Review — CROI 2017, Seattle

The Conference on Retroviruses and Opportunistic Infections (CROI) returned to Seattle this past week for its 24th meeting. It’s the 4th time CROI has been held in Seattle, an excellent city for a meeting of this size, which includes “only” 4200 people. The convention center is pleasant and user-friendly — big but not cavernous, actually encourages […]

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February 13th, 2017

How to Make Preventing Heart Disease in HIV Fun and Exciting: The REPRIEVE Trial

The people researching cardiovascular disease in HIV have quite the challenge. Because when you think about it for a second, we HIV treaters are a pretty spoiled bunch when it comes to therapeutic success. We saw the transformation of a terrifying, incurable, and rapidly progressive disease (AIDS) into something that can be managed for decades — usually with just […]

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February 5th, 2017

Case Report of PrEP Failure: What Can We Learn From It?

The New England Journal of Medicine has published the first well-documented case of HIV pre-exposure prophylaxis (PrEP) failure despite good medication adherence. We heard lots of this information at CROI last year, and again I’m impressed at the extraordinary degree of virologic investigation done on a case from clinical practice. To refresh your memory, here are the critical details from the […]

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