HIV and ID Observations

October 25th, 2020

(Not) Attending Professional Meetings in the COVID-19 Era

The Infectious Diseases Society of America (IDSA), our professional society, held its annual meeting this week, IDWeek. As usual, I registered for and attended the meeting. Of course I should have written “attended” the meeting, as instead of having an in-person meeting in Philadelphia (the original planned venue), it was entirely done online. Another “virtual” meeting […]

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October 18th, 2020

Does Remdesivir Actually Work?

Quick answer — it’s complicated. Let’s start with a clinical anecdote — rightfully considered the weakest form of evidence, yet paradoxically holding great power over us because we’re imperfect humans. It’s the way we’re wired. In April, a patient of mine with stable HIV came into the hospital with COVID-19 pneumonia. (Certain details changed for privacy.) She works […]

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October 4th, 2020

Does the White House Outbreak Invalidate the Strategy of Frequent Testing for COVID-19 Control?

As I’ve written here many times, I’m hopeful that frequent, inexpensive, rapid home testing for COVID-19 will help us climb out of this pandemic mess. Let’s name it the Mina Frequent Testing Plan, after my indefatigable colleague Dr. Michael Mina who has championed it for months — most recently in a perspective published in the New […]

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September 27th, 2020

Humbled — But Still Hopeful

When Dr. Anthony Fauci joined us earlier this month for a virtual medical grand rounds, several of my colleagues participated. At the end, each was asked to comment about what they had learned so far from the COVID-19 pandemic. Dr. Michael Klompas, our brilliant hospital epidemiologist, wisely answered: Humility. His answer resonated strongly again, because this week […]

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September 20th, 2020

Sports During COVID-19 — When What Doesn’t Matter Actually Matters a Lot

A few weeks ago, I got a text from a long-time ID colleague here in Boston: Hey Paul want ur opinion … this is for an interview with MLB radio, and no one knows less about baseball than I do, but as an avid fan and wise ID doc, do you think the season should continue? […]

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September 13th, 2020

Restaurants Are Hurting — But Dining Indoors Poses Real COVID-19 Risk

As we learn more about transmission of SARS-CoV-2, the news for restaurants goes from bad to worse. And while there’s a long list of sad things about this pandemic, the decimation of the restaurant business for owners and the people who work there is right up there. The loss of the restaurant experience for us diners […]

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September 7th, 2020

Relieving the COVID-19 Testing Logjam by Separating the Symptomatic from Asymptomatic

As the days grow shorter and we celebrate Labor Day here in the United States, the end of summer looms awfully near. With that will soon come colder temperatures, more time spent indoors, kids back in school, and the inevitable respiratory virus season. How we address these “viral URIs” in the midst of the COVID-19 pandemic […]

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August 30th, 2020

Cases of SARS-CoV-2 Reinfection Highlight the Limitations — and the Mysteries — of Our Immune System

In case you didn’t notice, or perhaps were “off the grid” taking some well-earned time away from COVID-19 news, this past week we heard about several cases of SARS-CoV-2 reinfection. We’ll come back to them in a moment, but first, some questions: Why does one parent never get sick when their kids start coughing and sneezing and […]

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August 16th, 2020

Picking the Top Internet ID Resources, and a Wistful Look Back at the CDC That Was

Over on Open Forum Infectious Diseases — and that’s abbreviated “O-F-I-D”, not “Oh-fid”, thank you — I sometimes invite other ID-types to join me on a podcast to pick their favorite ID-related item: Examples of these mock “drafts”: Antibiotics Landmark HIV research papers Expired antimicrobial brand names And some time this past winter (a million years ago), […]

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August 4th, 2020

Carbapenems and Pseudomonas, Lyme and Syphilis Testing, a Bonus Point for Doxycycline, and Some Other ID Stuff We’ve Been Talking About on Rounds

As noted multiple times, many of us ID doctors attend on the general medical service. This offers us a chance to broaden our patient care activities and to work with medical students, interns, and residents. Boy, that’s fun! Yes, those of us who attend on medicine enjoy it enormously, though the experience humbles us on a daily […]

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