HIV and ID Observations

June 28th, 2014

CDC Nixes HIV Western Blot in Latest Testing Guidelines

Finally, it’s official — the Western blot is no longer recommended as a confirmatory test for HIV infection. From the latest Laboratory Testing for the Diagnosis of HIV Infection, updated June 27: The HIV-1 Western blot and HIV-1 immunofluorescence assay, previously recommended to make a laboratory diagnosis of HIV-1 infection, are no longer part of the recommended algorithm. […]

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June 24th, 2014

At Long Last, Some New Antibiotics That Might Make a Difference

Compared to HIV, HCV, and antifungal agents, development of novel antibacterial drugs has been in a bit of a funk for quite some time now. Here’s what’s been approved in the past 10 years, with year of approval and a few comments: Telithromycin (2004):  The first ketolide antibiotic, it was supposed to overcome macrolide-resistant respiratory pathogens. But there were huge […]

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June 15th, 2014

Poll: Should ID Doctors Still Do HIV Primary Care?

My friend and colleague Ken Freedberg is giving a talk soon at our regional IDSA meeting called, “Who Should Be Providing HIV Care?” He’s a very smart guy (except during the football playoffs, when he is possessed by evil forces), so maybe he’ll answer this question that has strangely bedeviled our field for decades. But I’m sure […]

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June 4th, 2014

Anti-Vaccine Movement Slammed By Daily Show; ID Doctors, Pediatricians Happy

The anti-vaccine crowd gets a pretty good drubbing here from Samantha Bee on The Daily Show. I’d feel a tiny bit bad for them — gosh their opinions are pathetic — but since I’m an ID specialist married to a pediatrician, I can only rejoice in the brilliance of this piece. And yes, stupidity crosses political party lines. Enjoy! The Daily Show […]

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May 15th, 2014

CDC Recommends Broader Use of Pre-Exposure Prophylaxis — Can We Make It Happen?

Making a much stronger and more comprehensive statement than their earlier “Guidance,” the CDC is now recommending tenofovir/FTC (Truvada) for all Americans at high risk for HIV. More specifically, they recommend it for a broad range of people who have certain risk factors (click to see full size image): One certainly gets why this was done — as summarized nicely in […]

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May 3rd, 2014

The Top Items from the Revised DHHS HIV Treatment Guidelines

A sparkling, shiny new revision of the DHHS HIV Treatment Guidelines was released this week (thanks Alice Pau!), and provides plenty to read and think about — 285 pages, if you’re counting. A few ways to navigate this gargantuan effort more efficiently — the What’s New section, the recommendations summarized here, and the tables here. But if you want the […]

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April 27th, 2014

Why ID/HIV Specialists Rank Last in MD Salaries

Here’s a figure from Medscape listing 2013 physician compensation: Now a median of $174,000/year is hardly chump change, so I don’t expect much in the way of sympathy on these data. On the other hand, someone has to to be last, and note that our income hasn’t increased a bit since the last time I commented […]

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April 24th, 2014

Pioneering Measles Vaccine Researcher Has Anecdotes, Insight, Perspective, and Generosity to Spare

In the new IDSA/Oxford University Press journal Open Forum Infectious Diseases (OFID), we plan to interview a series of great figures in ID about their experiences, posting them as podcasts with accompanying scripts. Our first interview is with Dr. Samuel Katz, a key figure in development of the measles vaccine, and it can be heard here. […]

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April 12th, 2014

Unwittingly, HCV “News” Brackets Our Current Treatment Era on Successive Days

I’ve already told you what a fan I am of Physician’s First Watch, the daily email summary of hot medical news provided by my colleagues here at the Massachusetts Medical Society. If you haven’t signed up, you must do so — let’s play a short tune (always a favorite) for background music while you head over […]

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March 10th, 2014

CROI Is Over — and a Baby Once Again Takes Center Stage

One of our fellows asked me this AM when I was posting a RRR (Really Rapid Review™) of CROI 2014, and my response was to clear my throat, make some vague excuses, and curse the respiratory viruses that seem as perpetual as the cold weather this year. It’s in the works, promise — but in the […]

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