HIV and ID Observations

April 29th, 2018

ID Learning Unit: Clinically Important Streptococcal Infections You Need to Know

As mentioned last week, I’m currently attending on the general medical service, a chance to brush up on non-ID clinical skills, and more importantly, to work with smart, energetic house staff and medical students. Not surprisingly, there’s a wide range of clinical ID on this service, and this year we’ve had a rash of streptococcal infections. (Get […]

---

April 22nd, 2018

Some ID Stuff We’re Talking About on Medical Rounds — with Bonus Andy Borowitz Podcast

As an infectious diseases specialist attending on the general medical service each year, I am the beneficiary of a wonderful knowledge exchange. The smart house staff and my generalist co-attending teach me the latest about hyperkalemia, anticoagulation, anemia, alcohol withdrawal, acute renal injury, COPD, atrial fibrillation, pancreatitis, asthma, diabetes, and congestive heart failure — to name […]

---

April 16th, 2018

Hepatitis C Positive Organ Donors — Coming Soon to a Transplant Center Near You

There’s one immutable fact in solid organ transplantation — the number of patients awaiting transplant exceeds the number of available organs. This shortage means that ethical, medically safe strategies to increase the donor pool are always a high priority. One such strategy would be to allow transplants from people who have chronic hepatitis C. If the thought of […]

---

April 8th, 2018

Latest DHHS Guidelines for Initial HIV Therapy Now Include 5 Choices — But Really 2 Are Best

On March 28, the Department of Health and Human Services Guidelines issued an update to the HIV treatment guidelines, with a focus on the recent approval of bictegravir/TAF/FTC: BIC/TAF/FTC is an effective and well-tolerated INSTI-based regimen for initial therapy in adults with HIV, with efficacy that is noninferior to DTG/ABC/3TC and DTG plus TAF/FTC for up […]

---

April 1st, 2018

News Flash — The World Isn’t Sterile

You might have missed this press release from the National Institute of Allergy and Infectious Diseases (NIAID): Bethesda, MD April 1, 2018 The National Institute of Allergy and Infectious Diseases, at the National Institutes of Health, invites grant applications which propose research in the following 3 critical world health challenges: 1.  Development of an effective HIV […]

---

March 25th, 2018

Why Is Some Academic Spam Funnier Than Others?

This invitation made me laugh out loud: From: International Journal of Poultry and Fisheries Sciences <poultry@symbiosisonline.us> Date: Friday, March 23, 2018 at 7:03 AM To: “Sax, Paul Edward,M.D.” Subject: Accepting Articles for our Inaugural Issue: IJPFS  Dear Dr. Paul E Sax, Greetings from International Journal of Poultry and Fisheries Sciences! We are privileged to introduce International Journal of Poultry and Fisheries […]

---

March 18th, 2018

Why with Extremely Resistant Infections, It’s Extremely Important to Consult ID

Since the only procedures most of us Infectious Diseases doctors do with any regularity are biopsies of patient medical records, we have to justify our existence in other ways — such as collecting data on how our expertise improves patient outcomes. There are a bunch of these papers published, with this one being the most widely […]

---

March 11th, 2018

Really Rapid Review — CROI 2018, Boston

The 25th Conference on Retroviruses and Opportunistic Infections (CROI) just wrapped up in warm, sunny Boston. Everyone in attendance took advantage of the fine March weather to get some much-needed sun, to feel the sand between their toes, to sip a tropical drink, and to hear the latest in HIV research. Well, the last part was true […]

---

March 4th, 2018

Winner of ID Cartoon Caption Contest #3, and Here’s #4 Just in Time for CROI

One of the challenging aspects of writing this blog is that there is so much interesting material in the ID/HIV world that sometimes I forget to cover critical items. Example: the winner of the most recent ID Cartoon Caption Contest, which I’m embarrassed to admit, has been awaiting its announcement since late 2016. The winner: It’s a great […]

---

February 25th, 2018

Is Self-Administered Postexposure Prophylaxis Another Viable Option for HIV Prevention?

Most of the pivotal trials of pre-exposure prophylaxis (PrEP) have used daily therapy. The lone exception is the IPERGAY study. Men at high risk for acquiring HIV took two tablets of tenofovir DF/emtricitabine (TDF/FTC, Truvada) before sex, and one tablet the next 2 days. The strategy was highly effective in preventing HIV acquisition, and intermittent PrEP is endorsed […]

---