HIV and ID Observations

November 4th, 2018

Your Next ID Cartoon Caption Contest — Yearning for Your Submission

The nice people who write our hospital’s newsletter interviewed me recently about this blog, and we covered a whole lot of territory. How it got started … inspirations … popular posts … fax machines … why an ID doctor from Mexico asked me about my dog Louie. There was, however, a grave omission — nowhere in this […]

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October 28th, 2018

New Flu Drug Offers Convenience, Fast Activity, and a Novel Mechanism — at a Price

Last week, the FDA approved a new drug for treatment of influenza, baloxavir marboxil (Xofluza). The drug is indicated for treatment of symptomatic influenza in patients 12 years of age or older. As with existing treatments, it should be started within 48 hours of symptom onset. In a comparative clinical trial in otherwise healthy outpatients, baloxavir and oseltamivir […]

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October 21st, 2018

A Day in the Life of the Academic Assistant Professor of Medicine Who Wakes Up at 5:30 a.m. to Get Her Kids to School, Takes the Bus to Work, Answers Emails, Completes Online Required Modules, and Fills Out Disability Forms for Her Patients

(Inspired by a recent peculiar article about a Bay Area tech superstar.) Dr. Camilla Gormley is always on the move. From the moment her alarm wakes her at 5:30 a.m. to prepare breakfast and school lunches for her three kids, to the time 16-plus hours later when she can finally rest her head on her pillow, Dr. […]

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October 15th, 2018

Outpatient Antibiotic Prescribing Boosts Patient Satisfaction Scores, Rewarding Bad Medical Practice

A recent study confirms what every busy clinician already knows. Many patients seeking care for respiratory infections expect to receive an antibiotic. When they get one, they’re happier than if they don’t. Among 8437 patients seeking care for a respiratory tract infection in a direct-to-consumer telemedicine service, 66% received an antibiotic. The rate of prescriptions prescribed by […]

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October 8th, 2018

“Mini”-Really Rapid Review — IDWeek 2018, San Francisco

Once upon a time, the annual meeting of the Infectious Diseases Society of America (IDSA) wasn’t much of a research conference. It consisted mostly of review sessions on topics deemed worthy of an update or a refresher, led by noted experts in the field. They would cite the latest literature on endocarditis, or mycoplasma, or prosthetic […]

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October 2nd, 2018

Winner of Latest Cartoon Contest Proves Again That We ID Specialists Are a Different Breed

It is with a mixture of professional pride and embarrassment that I hereby present the winner of our last ID Cartoon Caption Contest: Yikes. Talk about inside jokes. Though the second-place finisher “Ah, no, I prescribed the AEROSOLIZED, not PARASOL-ized form” mounted a late charge, the geeky reference to Listeria monocytogenes and its “umbrella motility” held out for the win. […]

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September 23rd, 2018

Picking Your Next ID Journal Club Paper? MERINO or POET Trial? Two ID Fellows Debate

Late afternoon/early evening at an academic medical center. Bright young doctors sit in a hospital workroom, putting the finishing touches on what are undoubtedly the most comprehensive and, yes, simply the best consult notes in their respective patient’s electronic medical records.  Best ever. ID Fellow #1:  Hey, pretty soon we have to do Journal Club, right? ID […]

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September 16th, 2018

Supermarket Chain CEO Defends High Prices of Water, Salt, and Other Items as a “Moral” Requirement

Inspired by recent events in antibiotic pricing. SACRAMENTO, CA. The head of a national supermarket chain is defending a recent substantial increase in the price of water, salt, and other food and kitchen essentials, arguing that this change is the equivalent of a “moral” requirement. Last month, iFoods Plus Stores announced that common low-cost items such as […]

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September 9th, 2018

Doravirine Sets a New Standard for NNRTIs — But What Role in HIV Treatment Today?

The HIV drug class called “non-nucleoside reverse transcriptase inhibitors,” or NNRTIs, must have something of an inferiority complex. First, anything defined by what it is not is already in trouble. Believe me, hepatitis C was thrilled when it could shed the “non-A, non-B hepatitis” label. Second, despite their high antiviral potency and good tolerability, the NNRTIs have […]

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September 3rd, 2018

Eravacycline Approved by FDA — How Might It Be Used, Today and in the Future?

While last week the world was sunning on the beach, hiking in the woods, eating ice cream, and performing careful tick-checks, the hard workers at the Food and Drug Administration hunkered down in Silver Spring, Maryland to get three anti-infectives approved — eravacycline, doravirine, and doravirine/TDF/3TC. Maybe they saw the weather reports — hot and humid, this […]

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