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May 16th, 2016

Lots of College Graduations ID Link-O-Rama

For those of us living and working in Boston, we are most definitely smack dab in the middle of college graduation season — which means traffic is crazy, restaurants are booked, and energetic young adults are everywhere wearing gowns and funny hats. In other words, a good excuse for an ID Link-o-Rama: FDA advises against use of fluoroquinolones for uncomplicated […]


March 27th, 2016

One-Week-to-Baseball ID Link-o-Rama

(Important note:  Title has nothing to do with this post’s content. I just felt like writing something about baseball.) As some of us eagerly await the start of the 2016 baseball season — especially Cubs fans — here are some ID/HIV items yearning to shag flies, toss around the horsehide, and play some pepper: Famous anti-vaxxer — and notorious scientific fraud — […]


September 13th, 2015

Station Eleven Is a Very Good Read — Even for ID Doctors

One of my colleagues, an MD/PhD, stopped me after our clinical conference a few weeks ago. He does basic science research, doesn’t see patients anymore — but he still comes to our clinical conference. Definitely scores points for that. And for being a very smart, interesting, and nice fellow. This was our conversation, reproduced verbatim: HIM:  Hey Pablo […]


May 13th, 2015

WHO Guidelines on Naming Diseases Are Well-Meaning, Sensible — But Kind of Boring

From the World Health Organization (WHO), a recommendation on how to name a new disease: The best practices state that a disease name should consist of generic descriptive terms, based on the symptoms that the disease causes (e.g. respiratory disease, neurologic syndrome, watery diarrhoea) and more specific descriptive terms when robust information is available on how […]


March 28th, 2015

Quick Question: Should HIV-Negative People in Serodiscordant Relationships All Get PrEP?

From a very thoughtful and experienced primary care provider came this query: Hey Paul, quick question — One of my patients, an HIV-negative gay man, is in a long-term relationship with one of your HIV-positive patients — my patient says his partner has been on successful HIV treatment for years. Obviously I can’t check his partner’s […]


March 1st, 2015

Really Rapid Review — CROI 2015, Seattle

For the 3rd time in its illustrious history, the Conference on Retroviruses and Opportunistic Infections (CROI) returned to Seattle this past week for it’s 22nd meeting. For those of us living in the North Pole, 50 degrees and drizzle never felt so wonderful! (See image below for graphic representation — that’s my dog Louie wondering what happened to his world. […]


April 18th, 2012

Been There, Done That

I’d estimate the verisimilitude of the following video at approximately 100%: (Thanks to Raphy Landovitz for the link!)


August 3rd, 2011

Why the Proposed Massachusetts HIV Testing Bill is Bad for Patients

As I’ve written about here multiple times, I’m not a big fan of the HIV testing law in our state. First, there’s the requirement for written informed consent, something that every state (except a couple) has wisely abandoned. Second, it’s more than a testing law — it’s also an HIV privacy law, which is arguably unnecessary […]


April 25th, 2011

FEM-PrEP: A Set Back in HIV Prevention Research

HIV prevention has been on such a roll recently that the recent negative news from the FEM-PrEP study came as something of a surprise.  Bottom line: Following a scheduled interim review of the FEM-PrEP study data, the Independent Data Monitoring Committee (IDMC) advised that the FEM-PrEP study will be highly unlikely to be able to demonstrate […]


November 23rd, 2010

iPrEx: First-Ever PrEP Efficacy Study Published

It’s been quite the year (plus a month) for HIV prevention research. That glimmer of hope from the Thai vaccine trial.  The striking effect of HIV-treatment as prevention.  The positive results of the CAPRISA vaginal microbicide study, which were presented to rapturous applause this summer in Vienna. And today, the iPrEx study is published, which shows that giving TDF/FTC […]


HIV Information: Author Paul Sax, M.D.

Paul E. Sax, MD

Contributing Editor

NEJM Journal Watch
Infectious Diseases

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