HIV and ID Observations

April 21st, 2023

A Change-of-Season ID/HIV Link-o-Rama

The warm weather takes its sweet time to arrive here in Boston, teasing us with an occasional comfortable day, but reverting frequently to chilly temperatures and high winds until mid-to-late May at the earliest. The afternoon sunlight might say, “Spring is here!”, but the nightly temps in the upper 30s/low 40s definitely say otherwise. Brrr. Anyway, […]

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February 28th, 2023

Really Rapid Review — CROI 2023, Seattle

In a recent chat I had on a local TV network on this year’s respiratory virus season, the host mentioned that “this year felt very post-pandemic”, prompting me reflexively to knock wood — and I’m not a superstitious person. But even we ID doctors must acknowledge the dramatic improvement in COVID severity this winter compared to […]

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December 19th, 2022

Chaos in the Diagnosis of Pneumocystis Pneumonia

Confession — no one knows the best way to diagnose Pneumocystis jirovecii pneumonia, commonly abbreviated as PJP, or for some stubborn old timers, PCP. Don’t believe me? Take a look at this poll — not just the results, but the extraordinary diversity of responses — then head on back here for a historical perspective sure to […]

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November 21st, 2022

Five ID Things to Be Grateful For, 2022 Edition

In what’s something of a holiday tradition on this site, I hereby present 5 ID things we can be grateful for as we prepare for the best holiday of the year. Why the best? Family and friends. A nice big meal, with something for everyone. (My family of four has two vegetarians — they have plenty […]

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September 8th, 2022

A Back To Work ID Link-o-Rama

A few nuggets are rattling around in the inbox post Labor Day, including this extraordinary photo of our family dogs Zelda, Zoe, and Louie, posing for their latest album cover. Woof! Besides, I haven’t done one of these Link-o-Ramas since January 11, 2021! That was either 20 months ago or 20 years, hard to keep track of […]

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August 8th, 2022

Long-Acting Injectable HIV Therapy for People Who Won’t Take ART?

HIV treatment is so spectacularly effective that you might be surprised to hear that some people with HIV still have uncontrolled viral replication. We HIV clinicians watch with frustration and sadness as they experience progressive immunodeficiency, complications from advanced HIV disease, hospitalizations, and HIV-related deaths. Plus, while viremic, they continue to risk transmitting the virus […]

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February 18th, 2022

A Return of Antiretroviral Rounds — What Regimen Would You Choose?

Years ago, back in the pre- and early internet days, one of the most popular features in the newsletter Journal Watch AIDS Clinical Care was something called Antiretroviral Rounds. We’d present a case, then have two expert discussants weigh in on what they would do. The link above is a case from ancient history — 1998! […]

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November 23rd, 2021

Gratitude for 40 Years of Progress in HIV Care and Research

I was working with one of our outstanding senior ID fellows in clinic last week, and she presented the case she’d just seen, a 54-year-old man with HIV (certain details changed for confidentiality): Will is doing great on [fill in one-pill daily regimen], missing no doses. He’s having some difficulty with sleep (his wife says he […]

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October 31st, 2021

Interesting and Important Studies from IAS 2021 and IDWeek That Caught My Eye

As noted in my previous post, attending virtual meetings poses some serious challenges. The biggest obstacle:  trying to do one’s regular job while periodically checking in (or more likely not checking in) on the meeting. And while I might have been able to pull off some Really Rapid Reviews© after a few virtual meetings, not so […]

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May 10th, 2021

Goodbye, Physician’s First Watch — We’re Really Going to Miss You

One of the great joys of life is working with great people, and for me, this includes frequent interactions with several skillful medical editors. They scan these posts for typos and awkward sentences, and warn me when I inadvertently include a copyrighted image or an inappropriate video. They also worked, until recently, for Physician’s First Watch, […]

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