November 24th, 2014
Selections from Richard Lehman’s Literature Review: November 24th
Richard Lehman, BM, BCh, MRCGP
This week’s topics include the PROTECT-AF trial, the association of inpatient vs. outpatient onset of STEMI with treatment and clinical outcomes, and more.
September 8th, 2014
Selections from Richard Lehman’s Literature Review: September 8th
Richard Lehman, BM, BCh, MRCGP
This week’s topics include the PARADIGM-HF trial, sham controls in medical-device trials, the efficacy of β blockers in patients with heart failure and atrial fibrillation, and more.
August 1st, 2014
Noncardiac Surgery Guidelines Updated
Larry Husten, PHD
The reliability of current guidelines regarding perioperative evaluation and treatment of people undergoing noncardiac surgery has been seriously questioned because of a scandal discrediting Don Poldermans, a Dutch researcher widely published in the field. To address the current uncertainty, U.S. and European medical societies today released updated versions of these guidelines. The European guideline can be […]
March 10th, 2014
Selections from Richard Lehman’s Literature Review: March 10th
Richard Lehman, BM, BCh, MRCGP
This week’s topics include cognitive function and brain structure in type 2 diabetics after intensive lowering of BP and lipid levels, the association of β-blocker therapy with risks of adverse CV events and deaths in those with ischemic heart disease undergoing noncardiac surgery, and more.
January 6th, 2014
Selections from Richard Lehman’s Literature Review: January 6th
Richard Lehman, BM, BCh, MRCGP
This week’s topics include the NAVIGATOR study, trials of stents, mitral valve repair vs. replacement, and more.
October 4th, 2013
A New Use for an Old Beta-Blocker?
Borja Ibanez, MD PhD
Borja Ibañez, lead investigator of the METOCARD-CNIC trial, discusses the effect of intravenous beta-blocker use before reperfusion in patients undergoing primary PCI.
September 16th, 2013
Selections from Richard Lehman’s Literature Review: September 16th
Richard Lehman, BM, BCh, MRCGP
This week’s topics include the AMPLIFY trial, D2B time and mortality among those undergoing primary PCI, and more.
July 31st, 2013
European Heart Guidelines Based on Disgraced Research May Have Caused Thousands of Deaths
Larry Husten, PHD
Despite a 2-year-old scandal discrediting key evidence, current guidelines relying on this evidence have not been revised. As a result of physicians following these guidelines, some researchers say, it is possible that thousands of patients may have died each year in the U.K. alone. It is unlikely that a true understanding of the damage will […]
April 23rd, 2013
Study Suggests Benefit for Beta Blockers During Noncardiac Surgery
Larry Husten, PHD
The use of perioperative beta-blockade for noncardiac surgery has been declining as a result of the controversial POISE study, which turned up evidence for harm associated with extended-release metoprolol in this setting. Now a large new observational study published in JAMA offers a contrary perspective by suggesting that perioperative beta-blockade may be beneficial in low- […]
February 4th, 2013
Selections from Richard Lehman’s Literature Review: February 4th
Richard Lehman, BM, BCh, MRCGP
This week’s topics include blood transfusion and increased mortality in MI, proteotoxicity and cardiac dysfunction in the elderly, combined fitness and statin treatment on mortality in veterans with dyslipidemia, and more.
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