CardioExchange Archive

June 9th, 2014

Selections from Richard Lehman’s Literature Review: June 9th

Richard Lehman, BM, BCh, MRCGP

This week’s topics include the CORONARY trial, the association of azithromycin with mortality and CV events among older patients hospitalized with pneumonia, and more.

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May 18th, 2014

Statins Disappoint In COPD And ARDS

Larry Husten, PHD

Two NHLBI studies have failed to find any benefit for statin therapy in patients with chronic obstructive pulmonary disease (COPD) and acute respiratory distress syndrome (ARDS). Previous observational studies had raised the possibility that statins, perhaps due to their anti-inflammatory effects, might improve outcomes in people with these serious diseases. But both trials were stopped early by […]

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January 6th, 2014

Selections from Richard Lehman’s Literature Review: January 6th

Richard Lehman, BM, BCh, MRCGP

This week’s topics include the NAVIGATOR study, trials of stents, mitral valve repair vs. replacement, and more.

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May 20th, 2013

Similar Cardiovascular Risk Observed with COPD Drugs

Larry Husten, PHD

A large observational study has found no difference in the increased risk for cardiovascular disease between the two main classes of drugs used in the first-line treatment of chronic obstructive pulmonary disease (COPD). LABAs (long-acting inhaled beta-agonists) and LAMAs (long-acting muscarinic antagonists) have a variety of beneficial effects in COPD patients, but evidence has been […]

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March 22nd, 2013

Macrolide Antibiotic Linked to Increased CV Risk in Patients with Lung Conditions

Nicholas Downing, MD

Use of the macrolide clarithromycin in patients admitted with exacerbations of chronic obstructive pulmonary disease or community-acquired pneumonia is associated with increased risk for cardiovascular events, a BMJ study finds. Researchers examined outcomes among nearly 3000 patients admitted to U.K. hospitals with either condition. During 1 year of follow-up, there were roughly 450 new admissions for […]

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