CardioExchange Archive

September 17th, 2012

Selections from Richard Lehman’s Literature Review: September 17th

Richard Lehman, BM, BCh, MRCGP

This week’s topics include surgical vs. lifestyle treatment for type-2 diabetes, omega-3 fatty-acid supplementation and the risk for major CVD events, FAME 2, using high-sensitivity cardiac troponin T for one-hour rule-out or rule-in of acute MI, and the timing of acute MI in patients having total hip or knee replacement.

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June 11th, 2012

Selections from Richard Lehman’s Literature Review: June 11th

Richard Lehman, BM, BCh, MRCGP

This week’s topics include two studies of prognosis: troponin and mortality after non-cardiac surgery and predictors of heart-failure mortality.

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June 5th, 2012

Troponin T Test Helps Assess Mortality Risk Following Noncardiac Surgery

Larry Husten, PHD

A new study in JAMA finds that postoperative troponin T (TnT) tests can independently improve 30-day-mortality risk assessment among patients who have undergone noncardiac surgery. The VISION (Vascular Events in Noncardiac Surgery Patients Cohort Evaluation) study investigators evaluated the prognostic power of postoperative fourth-generation TnT testing in 15,133 patients. Overall mortality at 30 days was 1.9%. Some 11.6% of patients […]

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September 28th, 2011

Troponin Elevation in Skeletal Muscle Disease: Vindication for the Consulting Cardiologist?

Beth Waldron, MA

In an elegant study that will resonate with the anecdotal experience of many consulting cardiologists, Jaffe and colleagues provide strongly suggestive evidence that elevations in “cardiac” troponin T may not be quite as specific for cardiac muscle injury as has been claimed (see CardioExchange News blog). Among patients with skeletal myopathies who had elevations in […]

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September 28th, 2011

Study Finds Noncardiac Sources of Positive Troponin T Tests

Larry Husten, PHD

Cardiac troponin T (cTnT) is not always cardiac specific and in some cases may lead to a false-positive diagnosis of cardiac injury, according to a study in the Journal of the American College of Cardiology. The study was prompted by a case seen by a senior clinician at the Mayo Clinic in which a patient, who was […]

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