July 2nd, 2013
Hundreds of Questions About the Integrity of Stem-Cell Research Group
Larry Husten, PHD
Serious questions have been raised about the integrity and validity of research conducted by a well-established German stem-cell research group. An article in the International Journal of Cardiology exhaustively details a multitude of discrepancies and contradictions in papers from the group. Further, the revelation of such widespread misconduct may lead to broader, disturbing questions about the reliability of […]
December 17th, 2012
Selections from Richard Lehman’s Literature Review: December 17th
Richard Lehman, BM, BCh, MRCGP
This week’s topics include a study on ICD programming to reduce inappropriate therapy and mortality, a clinical review of diagnosing and managing supraventricular tachycardia, the Global Burden of Disease Study 2010, and more.
July 5th, 2012
Stem Cell Therapy Company Hypes Preliminary Results
Larry Husten, PHD
A biotech company has been accused of releasing preliminary and misleading information about a clinical trial. The company, Osiris Therapeutics, is the manufacturer of a cultured mesenchymal stem cell (MSC) therapy called Prochymal, which is being studied in a phase 2, placebo-controlled trial in post-MI patients. Earlier this week, Osiris issued a press release announcing preliminary results from the trial, in […]
April 30th, 2012
Selections from Richard Lehman’s Literature Review: Week of April 30th
Richard Lehman, BM, BCh, MRCGP
This week, Richard looks at endocarditis and ICDs, more stent wars, stroke prevention in A-Fib, and more.
November 15th, 2011
Hype Aside, Hope for Stem Cell Therapy May Be Emerging from Hibernation
Larry Husten, PHD
Two small studies of cardiac stem cells for the treatment of heart failure have shown promise, but ABC News, CBS News, and other media outlets are throwing around words like “medical breakthrough” and “heart failure cure.” ABC News correspondent Richard Besser was so enthusiastic that anchor Diane Sawyer commented that she had never seen him “so excited.” […]
March 17th, 2011
Small Study May Help Revive Hope for Stem Cell Therapy
Larry Husten, PHD
Stem cell therapy may help reverse long-term damage after MI, according to a small, preliminary study by a group led by Joshua Hare published in Circulation: Research. Eight patients with LV dysfunction after MI received injections of autologous bone marrow progenitor cells in the LV scar and surrounding area. At one year, as assessed by […]