May 2nd, 2013
A large observational study found no increased risk for cardiovascular events associated with azithromycin (Zithromax, Pfizer) in a general population of young and middle-age adults. In a paper published in the New England Journal of Medicine, Danish investigators report the results of a large national observational study comparing people who took azithromycin with matched controls […]
March 15th, 2013
When I am faced with a patient who needs an antibiotic, and there is an alternative antibiotic with similar efficacy and lower QT risk, I will choose the antibiotic with lower QT risk, and I’m especially careful with patients with certain characteristics that put them at increased risk.
January 29th, 2013
In August 2011 the FDA issued a safety communication recommending that the extremely popular antidepressant citalopram (Celexa) not be used at doses greater than 40 mg/day because of a potential increased risk for serious cardiac arrhythmias associated with prolongation of the QT interval. Now a study published in BMJ lends support to this warning and suggests that other antidepressants may […]