CardioExchange Archive

May 2nd, 2013

Danish Study Finds No Increased CV Risk with Azithromycin in General Population

Larry Husten, PHD

A large observational study found no increased risk for cardiovascular events associated with azithromycin (Zithromax, Pfizer) in a general population of young and middle-age adults. In a paper published in the New England Journal of Medicine, Danish investigators report the results of a large national observational study comparing people who took azithromycin with matched controls […]

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March 15th, 2013

Azithro a No Go?

Richard Joseph Kovacs, MD

When I am faced with a patient who needs an antibiotic, and there is an alternative antibiotic with similar efficacy and lower QT risk, I will choose the antibiotic with lower QT risk, and I’m especially careful with patients with certain characteristics that put them at increased risk.

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January 29th, 2013

Popular Antidepressants May Prolong QT Interval

Larry Husten, PHD

In August 2011 the FDA issued a safety communication recommending that the extremely popular antidepressant citalopram (Celexa) not be used at doses greater than 40 mg/day because of a potential increased risk for serious cardiac arrhythmias associated with prolongation of the QT interval. Now a study published in BMJ lends support to this warning and suggests that other antidepressants may […]

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