Posts Tagged ‘left main disease’

September 8th, 2014

Anteroseptal MI and Left-Main Dissection in a Pregnant Woman


Harsh Golwala presents our latest case: A 25-year-old woman, 32 weeks pregnant, presents with sudden-onset chest pain. How do you proceed?

February 22nd, 2013

SYNTAX After 5 Years: Any Change in Results (or Your Practice)?


The 5 year results of the SYNTAX (SYNergy between percutaneous coronary intervention with TAXus and cardiac surgery) trial are now published.  SYNTAX assessed the optimal revascularization strategy for patients with left main and/or 3-vessel disease by randomly assigning such patients to CABG or PCI (with a first-generation paclitaxel-eluting stent) and then determining the rate of […]

April 12th, 2012

Ascertaining ASCERT: How Well Do Registry Data Measure Up to the ‘Bedside Test’?

In the ASCERT observational study, stable patients (age 65 or older) with double- or triple-vessel CAD, but not left-main disease, were found to have better long-term survival after CABG than after PCI. ASCERT was a laudable achievement in terms of its scope and the level of collaboration it represents. The ASCERT investigators used inverse probability weighting (propensity […]

April 4th, 2011

PRECOMBAT Explores PCI Versus CABG for Left Main Disease

In the PRECOMBAT trial, Korean investigators randomized 600 patients with unprotected left main disease to either PCI with a sirolimus-eluting stent or CABG. The results were presented at the ACC and published simultaneously in the New England Journal of Medicine. At 1 year, the incidence of the primary composite endpoint – death from any cause, MI, […]