CardioExchange Archive

August 19th, 2014

Do Patients Really Have to Fast Before Lipid Testing?

Sripal Bangalore, MD, MHA

Harlan Krumholz interviews Sripal Bangalore about his research group’s study of the prognostic value of non-fasting lipid panels.

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August 18th, 2014

Advice on Implementing the New Cholesterol Guidelines

Sidney C. Smith, MD

CardioExchange’s Harlan M. Krumholz interviews Sidney C. Smith, coauthor of a new article, published in JACC, that reviews the major findings and recommendations of the 2013 cholesterol guidelines, as well as the recommendations’ implications for risk assessment, LDL lowering, and statin use. Krumholz: How have the new guidelines changed your practice?  Smith: The new focus on statins, […]

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August 4th, 2014

Plant-Based Diet, Healthy Heart?

Kim Williams, MD and Harlan M. Krumholz, MD, SM

Kim Williams shares with Harlan Krumholz how a patient inspired him to try a plant-based diet, how it has improved his health, and why he now recommends it to his patients.

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July 31st, 2014

What Does CRISPR’s Success Mean for Cholesterol Control?

Anthony L Komaroff, MD

CRISPR is a new technique for inactivating or editing specific genes. Developed in microorganisms, it also works in mammalian cells, including in vitro human cells and monkey embryos. About 10 years ago, a gene was identified that is critical to production of the LDL cholesterol receptor (LDL-R): PCSK9. Naturally occurring human mutations that enhance the effect […]

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April 30th, 2014

Thinking About Risk

John E Brush, MD

John E. Brush discusses new ways to help patients consider their cardiovascular risk.

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November 20th, 2013

AHA.13: Good until the End

Seth Shay Martin, MD

On the last afternoon at AHA.13, a poster on an experimental preventive treatment catches the eye of a cardiology Fellow .

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November 7th, 2013

FDA Seeks to Eliminate Trans Fat from Food in the U.S.

Larry Husten, PHD

The FDA said today that it would begin to take efforts to remove trans fat from food in the U.S. The agency has made the “preliminary determination that partially hydrogenated oils (PHOs), the primary dietary source of artificial trans fat in processed foods, are not ‘generally recognized as safe’ for use in food.” If the FDA’s preliminary determination is made final then manufacturers […]

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August 14th, 2013

Advanced Lipoprotein Analysis: Time for Widespread Implementation?

Behnood Bikdeli, M.D.

Will advanced lipoprotein analysis add real value to patients’ lives?

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April 29th, 2013

Unconventional Analysis Finds Threshold for LDL Reduction with Statins

Larry Husten, PHD

Using an unconventional mathematical approach, a group of Japanese researchers say there may be no good reason to reduce LDL cholesterol more than 40 mg/dl. Their research letter has been published online in JAMA Internal Medicine. According to the authors, members of the ALICE (All-Literature Investigation of Cardiovascular Evidence) Group, most meta-analyses use linear models that […]

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February 21st, 2013

Study Casts Doubt on Value of Genetic Testing for Familial Hypercholesterolemia

Larry Husten, PHD

The recent introduction of two drugs specifically targeted to treat people with the rare but dangerous condition of homozygous familial hypercholesterolemia (FH) has caused increased interest in figuring out the best strategy to identify people with the disorder. Now a new study published online in the Lancet suggests that one of the main screening plans that relies on genetic […]

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