January 29th, 2013
In REGARDS to Depression, MI, and Death in Patients with CHD
Monika Safford discusses the behavioral mechanisms that most contribute to the association between depression and MI or death in those with CHD.
October 29th, 2012
Selections from Richard Lehman’s Literature Review: October 29th
Richard Lehman, BM, BCh, MRCGP
This week’s topics include CV risk factors and peripheral artery disease in men, radiofrequency ablation in paroxysmal AF, CPR duration and survival after in-hospital cardiac arrest, an everolimus-eluting stent vs. a bare-metal stent in STEMI, job strain and CHD, and more.
October 18th, 2012
Should Hypercholesterolemia Treatments Start Much Sooner in Life?
Keeping LDL cholesterol low throughout life is more effective at preventing atherosclerotic disease than starting statins in middle age, a series of analyses in the Journal of the American College of Cardiology shows. Researchers first established the effects of several genetic variations on naturally lowering LDL. People with one or more of these variants had their […]
March 15th, 2012
Strongest Evidence to Date for Causative Role of Inflammation in Heart Disease
Larry Husten, PHD
Two large new meta-analyses published in the Lancet provide the first strong evidence demonstrating a cause-effect relationship between a specific inflammatory protein and the development of coronary heart disease (CHD). Both studies illuminate the role of interleukin-6 receptor (IL6R) by focusing on the common Asp358Ala variant of the IL6R gene. The variant is known to dampen the inflammatory effect […]