April 16th, 2013
Small Study Links Left Anterior Fascicular Block to AF and CHF
Larry Husten, PHD
In people without known cardiovascular (CV) disease the presence of left anterior fascicular block (LAFB) has not been thought to indicate increased risk. Now a research letter published in JAMA finds evidence that elderly people with LAFB are more likely to die and to develop atrial fibrillation (AF) and congestive heart failure (CHF) than people without LAFB. […]
November 14th, 2010
ICD-CRT Found Beneficial in RAFT
Larry Husten, PHD
RAFT (Resynchronization-Defibrillation for Ambulatory Heart Failure Trial) randomized 1798 patients with NYHA class II or III heart failure, LVEF < 30%, and a wide QRS complex to either an ICD alone or an ICD-CRT. After a mean followup of 40 months, the rate of death or heart failure hospitalization was 40.3% in the ICD group […]
October 7th, 2010
Rolofylline Fails in Heart-Failure Trial
Larry Husten, PHD
In a report in the New England Journal of Medicine, Massie and colleagues randomized 2033 patients hospitalized with acute heart failure and impaired renal function to receive intravenous roloflylline or placebo. Earlier studies had suggested that the use of an adenosine A1-receptor antagonist might be beneficial in this patient population. There was no difference between the […]
NEJM Journal Watch — Recent Cardiology Articles- GLP-1 Agonists and SGLT-2 Inhibitors Together Have Greater Cardiorenal Benefits
- More Data Support Semaglutide for Obesity-Related HFpEF, Regardless of Diabetes Diagnosis
- A Novel Agent Fails to Improve Outcomes in Diabetic Cardiomyopathy
- Persistent Symptoms After Valve Replacement for Severe Aortic Stenosis
- Is Diltiazem Safe in Patients with AF Taking Apixaban or Rivaroxaban?