CardioExchange Archive

April 6th, 2015

Cardiac Arrest During Exercise in Middle-Aged People

Larry Husten, PHD

Dropping dead while exercising is a common fear, especially among middle-aged men. Unfortunately there have been limited data on the precise rate of sudden cardiac arrest (SCA) in middle-aged people and little understanding about the medical history of the victims of SCA. Now a new study fills in some important gaps in knowledge and shows that this […]

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March 23rd, 2015

Dangerous Interaction: New Hepatitis C Drug and Old Arrhythmia Drug

Larry Husten, PHD

Late last week Gilead Sciences issued a warning about a rare but potentially fatal interaction between its stellar new hepatitis C drug sofosbuvir and amiodarone, a potent but tricky antiarrhythmic agent. Sofosbuvir is marketed as Sovaldi and, in combination with another antiviral agent, as Harvoni. Amiodarone is a class III antiarrhythmic with a number of […]

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December 1st, 2014

Study Suggests Epinephrine for Cardiac Arrest May Be Harmful

Larry Husten, PHD

Epinephrine has been a cornerstone of therapy during cardiac resuscitation after cardiac arrest because of its well-established ability to stimulate the heart and increase the probability of a return of spontaneous circulation (ROSC). In recent years, however, concerns have been raised that people treated with epinephrine may have worse neurological outcomes following their resuscitation. In a […]

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September 11th, 2014

Is This Trial Ethical?

CardioExchange Editors, Staff

Does the need for a new placebo-controlled trial of epinephrine in cardiac arrest justify questionable consent procedures?

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January 6th, 2014

Selections from Richard Lehman’s Literature Review: January 6th

Richard Lehman, BM, BCh, MRCGP

This week’s topics include the NAVIGATOR study, trials of stents, mitral valve repair vs. replacement, and more.

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December 9th, 2013

Selections from Richard Lehman’s Literature Review: December 9th

Richard Lehman, BM, BCh, MRCGP

This week’s topics include targeted temperature management after cardiac arrest, the safety and efficacy of DES in women, and more.

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September 9th, 2013

Clear! CPR in the Hospital Is Not Always Good for the Patient

Larry Husten, PHD

On TV it always seems clear and simple. A patient in the hospital goes into cardiac arrest and the medical team springs into action. After a few tense moments of furious activity, and only after all seems lost, the patient is successfully revived. A few scenes later the smiling and now fully healthy patient thanks […]

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July 25th, 2013

Vasopressin-Epinephrine Plus Corticosteroids Improve Neurologic Status After In-Hospital Cardiac Arrest – Implications for Out-of-Hospital Arrest?

Graham Nichol, MD MPH

Graham Nichol takes a close look at a recent randomized trial that examined whether combined vasopressin-epinephrine plus corticosteroids during CPR could improve survival and neurologic status in patients with in-hospital cardiac arrest.

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September 6th, 2012

Resuscitating Resuscitation

Brahmajee Kartik Nallamothu, MD, MPH and Zachary Goldberger, MD, MS

Lancet authors Brahmajee Nallamothu and Zarchary Goldberger join CardioExchange to answer questions about their provocative study indicating a correlation between prolonged resuscitation efforts and survival.

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July 12th, 2012

Selections from Richard Lehman’s Literature Review: July 12th

Richard Lehman, BM, BCh, MRCGP

This week’s topics include sex differences in the protective effect of statins, an action measure to lower BP among diabetics, a prediction tool for initial survivors of in-hospital cardiac arrest, the diagnosis and treatment of pulmonary embolism, an intervention to prevent medication errors after hospital discharge, and rehospitalization after acute MI.

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