Posts Tagged ‘ASCEND-HF’

September 30th, 2013

Nesiritide Does Not Increase Diuresis in ADHF Patients

Stephen Gottlieb discusses his research group’s analysis of ASCEND-HF data, which shows that nesiritide does not increase urine output in patients with ADHF.

November 30th, 2010

ASCENDing Into the Depths of the Nesiritide Controversy: Questions for Eugene Braunwald

Results of ASCEND-HF (Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure Trial), presented as a late-breaking clinical trial at the AHA meeting, showed that there were no significant differences in the pre-specified endpoint of dyspnea among some 7,000 patients with acute, decompensated HF randomized to receive standard therapy and either continuous intravenous nesiritide or placebo. This trial was started in […]