CardioExchange Archive

December 12th, 2012

AMPLIFYING Treatment for DVT/PE

John Ryan, MD

John Ryan reviews the latest data and suggests that DVT/PE be managed as a chronic condition. Are you using apixaban in these patients, and how long are you treating them for?

---

December 8th, 2012

Prolonged Anticoagulation with Apixaban Beneficial in Venous Thromboembolism

Larry Husten, PHD

A new study suggests that extending anticoagulant therapy for an additional year may be beneficial after patients with venous thromboembolism complete their initial course of therapy. The results of AMPLIFY-EXT (Apixaban after the Initial Management of Pulmonary Embolism and Deep Vein Thrombosis with First-Line Therapy-Extended Treatment) were presented at the annual meeting of the American Society […]

---

November 27th, 2012

Longer Warfarin Therapy After Bioprosthetic Aortic Valve Replacement May Be Beneficial

Larry Husten, PHD

Three months of warfarin is the usual standard of care following bioprosthetic aortic valve replacement (AVR),  although the supporting evidence base for this practice is limited. A new, large registry study published in JAMA suggests that more-prolonged warfarin therapy may be beneficial. Danish researchers identified 4075 patients who underwent bioprosthetic AVR. As expected, warfarin treatment between 30 and […]

---

October 15th, 2012

Stable Anticoagulation, Unstable Gait

Jeff Dickey, MD and James Fang, MD

A 91-year-old man with mild drug-controlled hypertension and atrial fibrillation has long-term, well-managed stability on warfarin anticoagulation. After developing problems with his balance and some gait instability, a physical exam reveals a carotid bruit. Carotid ultrasound and magnetic resonance angiography (MRA) confirm >95% stenosis of the right internal carotid artery. Brain CT is negative. Questions: 1.      […]

---

June 26th, 2012

Aspirin Reduces Risk for Recurrent VTE

John Ryan, MD and ceciliabecattini690

John Ryan interviews Cecelia Beccatini about her new study that found that aspirin treatment in patients with first-time unprovoked VTE resulted in a significant reduction in VTE but did not increase the risk for bleeding.

---

May 31st, 2012

Women at Increased Risk for Stroke in Atrial Fibrillation

Larry Husten, PHD

Among patients with atrial fibrillation (AF), women have a higher risk than men of having a stroke, according to a new study published in BMJ. The increased risk was mostly found in women over 65 years of age and in women with multiple risk factors. Leif Friberg and colleagues analyzed data from more than 100,000 Swedish patients with […]

---

May 24th, 2012

Aspirin Found to Prevent Recurrent Venous Thromboembolism

Larry Husten, PHD

Aspirin can help prevent the recurrence of venous thromboembolism (VTE) after discontinuation of anticoagulation therapy, according to results of the WARFASA (the Warfarin and Aspirin) study published in the New England Journal of Medicine. Following 6 to 18 months of oral anticoagulation, 403 patients with first-time unprovoked VTE were randomized to aspirin (100 mg daily) or placebo for 2 […]

---

May 6th, 2012

Patent Foramen Ovale — Are the Choices Patently Obvious?

Shelby Kutty, MD and John Ryan, MD

Shelby Kutty explains what we know and what we don’t know about how to manage patients with a PFO.

---

April 11th, 2012

Anticoagulation Conundrum

Tariq Ahmad, MD, MPH and James Fang, MD

A 75-year-old woman presents to a general cardiology clinic for the first time. She has a history of atrial fibrillation, sick-sinus syndrome requiring a permanent pacemaker, hypertension, and dyslipidemia. She has no specific complaints other than shortness of breath on exertion. Her medications include aspirin (81 mg daily), carvedilol (25 mg twice daily), lisinopril (5 […]

---

January 17th, 2012

Selections from Richard Lehman’s Weekly Review: Week of January 16th

Richard Lehman, BM, BCh, MRCGP

This week’s topics include acute MI and potassium levels, cardiac arrest during long-distance running, the anticoagulant idrabiotaparinux, and managing hypertension in the very elderly.

---