April 8th, 2014
Study Suggests Link Between Viagra and Melanoma
Larry Husten, PHD
In recent years, researchers have uncovered a potentially important pathway whereby PDE5A inhibitors (which include sildenafil — Viagra — and other drugs used to treat erectile dysfunction and pulmonary hypertension) could potentially increase the risk for developing melanoma. Now a study provides early evidence showing an association between sildenafil and melanoma, though, like all observational […]
March 12th, 2013
Sildenafil Does Not Improve Exercise Capacity in HF with Preserved Ejection Fraction
Nicholas Downing, MD
Sildenafil does not improve exercise capacity or clinical status in patients with symptomatic heart failure (HF) and preserved ejection fraction, according to a JAMA study. This finding contrasts with previous research suggesting a potential benefit in such patients. Some 220 HF patients with ejection fractions of 50% or greater were randomized to receive oral sildenafil or […]
NEJM Journal Watch — Recent Cardiology Articles- Does Lowering High Childhood Lipid Levels Prevent Adverse Cardiovascular Events in Adulthood?
- Self-Expanding Supraannular Valve vs. Balloon-Expandable Valve in TAVR for Small Aortic Annulus
- A New TAVR Prosthesis for Aortic Regurgitation Shows Promise
- Aprocitentan, a Newly Approved Drug for Resistant Hypertension
- Preventive PCI of Vulnerable Plaques Linked to Fewer Cardiac Events