December 9th, 2013
Selections from Richard Lehman’s Literature Review: December 9th
Richard Lehman, BM, BCh, MRCGP
This week’s topics include targeted temperature management after cardiac arrest, the safety and efficacy of DES in women, and more.
December 3rd, 2013
Stents Lose in Comparisons with Surgery and Medical Therapy
Larry Husten, PHD
Despite the enormous increase in the use of stents in recent decades, there is little or no good evidence comparing their use to the alternatives of CABG surgery or optimal medical therapy in patients also eligible for these strategies. Now two meta-analyses published in JAMA Internal Medicine provide new evidence that the alternatives to PCI […]
November 25th, 2013
Selections from Richard Lehman’s Literature Review: November 25th
Richard Lehman, BM, BCh, MRCGP
This week’s topics include DAPT cessation and coronary events after PCI, statins and cognitive function, and more.
October 21st, 2013
Refining the Optimal Duration of Dual Antiplatelet Therapy After DES Implantation
Cheol-Whan Lee, MD and Seung-Jung Park, MD.,Ph.D
Cheol Whan Lee and Seung-Jung Park discuss their study group’s randomized trial comparing dual antiplatelet therapy with aspirin alone beyond 12 months after drug-eluting stent implantation.
October 17th, 2013
New Insights Into Surgery vs. Stents for Diabetics with Multivessel Disease
Larry Husten, PHD
Last year the large NHLBI FREEDOM trial demonstrated that coronary-artery bypass graft (CABG) surgery was superior to PCI when treating diabetic patients who have multivessel coronary disease. CABG resulted in significant reductions in death and MI, but this was offset slightly by a higher rate of stroke in the CABG group. Now, a new report from FREEDOM […]
October 7th, 2013
Study Supports Loosening Guidelines for Surgery After Stent Implantation
Larry Husten, PHD
According to current guidelines, noncardiac surgery should be delayed for six weeks after bare-metal stent (BMS) implantation and for one year after drug-eluting stent (DES) implantation, though there is little good evidence to support these recommendations. Stent thrombosis caused by discontinuation of antiplatelet therapy in order to lower the risk of bleeding during surgery is the […]
October 4th, 2013
A New Use for an Old Beta-Blocker?
Borja Ibanez, MD PhD
Borja Ibañez, lead investigator of the METOCARD-CNIC trial, discusses the effect of intravenous beta-blocker use before reperfusion in patients undergoing primary PCI.
September 26th, 2013
Scrutinizing the PRAMI Trial of “Preventive Angioplasty”
Victor Montori, MD, MSc
Victor Montori offers his analysis of the PRAMI trial and the many ramifications of stopping an investigation early.
September 24th, 2013
A New Model to Predict Post-PCI Bleeding
Sunil Rao, MD
Sunil Rao discusses his research group’s risk model that uses an expanded definition of bleeding to predict which patients will have bleeding complications after PCI.
September 20th, 2013
My Stent Is Better Than Your Stent
Richard A. Lange, MD, MBA and L. David Hillis, MD
Interventionalists have many choices when it comes to coronary stents. Rick Lange and David Hillis want to know: “How do you decide which stent to use?”