August 18th, 2014
Radial Access for PCI in Women: A Registry-Based Randomized Trial
Sunil Rao, MD, Harlan M. Krumholz, MD, SM and John Ryan, MD
Harlan Krumholz and John Ryan interview Sunil Rao, lead author of SAFE-PCI for Women, a registry-based randomized trial of a radial versus a femoral approach to PCI.
July 11th, 2014
Do FFR and IVUS Feed the Elephant?
Richard A. Lange, MD, MBA and L. David Hillis, MD
Rick Lange and David Hillis wonder whether the debate about the role of FFR and IVUS in patient selection for PCI is a red herring in the larger issue of revascularization in patients with stable CAD.
June 30th, 2014
Registry Study Offers Reassurance About Newer Drug-Eluting Stents
Larry Husten, PHD
Findings from a large ongoing registry study provide some reassurance about the long-term safety of new-generation drug-eluting stents (DES) in patients with STEMI who undergo primary PCI. The results are published online in the Journal of the American College of Cardiology. SCAAR (Swedish Coronary Angiography and Angioplasty Registry) investigators analyzed data from 34,000 primary PCI patients who […]
June 30th, 2014
Selections from Richard Lehman’s Literature Review: June 30th
Richard Lehman, BM, BCh, MRCGP
This week’s topics include atrial fibrillation and cryptogenic stroke, higher potency statins and the risk for new diabetes, and more.
May 20th, 2014
Hopes and Beliefs: How Patients Respond to Informed-Consent Tools
Todd K. Rosengart, MD
Todd Rosengart answers Harlan Krumholz’s questions about his study of informed consent in patients scheduled for PCI.
May 19th, 2014
Lytics in STEMI: A New Analysis of Data from FAST-MI
Nicolas Danchin, MD, PhD and John Ryan, MD
French researchers analyze data from FAST-MI and conclude that a fibrinolysis-based strategy may be valid for some patients with STEMI.
February 25th, 2014
Study Raises Questions About Transfusions in PCI Patients
Larry Husten, PHD
A very large observational study raises important questions about the role of transfusions in PCI patients in the U.S. In a study published in JAMA, researchers from Duke and Yale analyzed data from more than 2.25 million percutaneous coronary intervention (PCI) procedures at more than 1400 hospitals. The data came from the CathPCI Registry, a large ongoing study […]
February 13th, 2014
FDA Advisory Panel Recommends Against Approval of Cangrelor
Larry Husten, PHD
The FDA’s Cardiovascular and Renal Drugs Advisory Committee today recommended against the approval of cangrelor, the investigational new antiplatelet drug from the Medicines Company. In a 7-2 vote, the panel first rejected an indication for the reduction of thrombotic cardiovascular events including stent thrombosis in patients undergoing PCI. The panel also voted unanimously to reject a second indication, for the […]
February 10th, 2014
Selections from Richard Lehman’s Literature Review: February 10th
Richard Lehman, BM, BCh, MRCGP
This week’s topics include two reports of cobalt-induced heart failure, a comparison of CABG and PCI, and more.
January 27th, 2014
How “Compelling” Are Coronary Anatomy and Ischemic Burden When Considering an Invasive Strategy?
William Edward Boden, MD
William E. Boden discusses his research group’s post hoc analysis of data from the COURAGE trial.