October 27th, 2014
Selections from Richard Lehman’s Literature Review: October 27th
Richard Lehman, BM, BCh, MRCGP
This week’s topics include behavioral counseling for those with CV risk factors, long-term outcomes after stenting vs. endarterectomy for treatment of symptomatic carotid stenosis, and more.
January 22nd, 2014
SERIES: Making Sense of the New Prevention Guidelines — The View from Clinical Practice
Harlan M. Krumholz, MD, SM
A series of clinical vignettes involving decisions affected by the recently published prevention guidelines (JNC 8, ACC/AHA, ESC)
September 16th, 2013
Intense Lifestyle Changes May Lengthen Telomeres
Larry Husten, PHD
A very small pilot study offers early evidence that a program of comprehensive lifestyle changes increases telomere length. Telomeres, which have been compared to the plastic caps that prevent shoelaces from unravelling, help protect chromosomes. Telomere length is closely correlated to cellular aging: as we age the telomeres in our cells grow shorter. The new study, published online […]
June 24th, 2013
Large NIH Trial Finds No Cardiovascular Benefits for Weight Loss and Exercise in Type 2 Diabetics
Larry Husten, PHD
A large NIH-sponsored trial has found that an intensive lifestyle intervention was no better than standard care in reducing cardiovascular events in people with type 2 diabetes. The results of the Look AHEAD trial were presented today at the American Diabetes Association meeting and published simultaneously in the New England Journal of Medicine. A total of 5,145 people with type 2 […]
December 27th, 2012
Selections from Richard Lehman’s Literature Review: December 27th
Richard Lehman, BM, BCh, MRCGP
This week’s topics include an intensive lifestyle intervention and its association with type-2 diabetes remission, strategies for multivessel revascularization in patients with diabetes, and more.
October 22nd, 2012
NIH Trial of Lifestyle Intervention for Type 2 Diabetes Stopped for Futility After 11 Years
Larry Husten, PHD
The NIH today announced the early termination of a large randomized trial testing a lifestyle intervention approach to weight loss in type 2 diabetics. More than 5,000 patients with type 2 diabetes were randomized to participate in an intensive lifestyle intervention program or a traditional program of diabetes support and education in Look AHEAD (Action for Health […]