August 15th, 2013
Remote Ischemic Preconditioning Beneficial Before CABG
Larry Husten, PHD
For several decades cardiologists have been intrigued by the concept of ischemic preconditioning. A small body of research has consistently found that brief episodes of ischemia appeared to somehow prepare the body to better handle a major episode of ischemia. Now a new study from Germany holds out the promise that deliberate ischemic preconditioning prior […]
March 10th, 2013
Cangrelor During PCI May Reduce Ischemic Events
Larry Husten, PHD
For more of our ACC.13 coverage of late-breaking clinical trials, interviews with the authors of the most important research, and blogs from our fellows on the most interesting presentations at the meeting, check out our Coverage Headquarters. In the Cangrelor versus Standard Therapy to Achieve Optimal Management of Platelet Inhibition (CHAMPION PHOENIX) trial, the intravenous platelet […]
November 16th, 2011
AHA Lessons on Emotions and Heart Disease: Depressing Data but Hopeful Trends
Amit Shah, MD, MSCR
Several Cardiology Fellows who are attending AHA.11 this week are blogging together on CardioExchange. The Fellows include Revathi Balakrishnan, Eiman Jahangir, John Ryan (moderator), and Amit Shah. Read the previous post here. Check back often to learn about the biggest buzz in Orlando. The many studies and sessions devoted to depression and heart disease at AHA — […]
August 9th, 2011
Will ISCHEMIA Tell Us More than COURAGE? PART II: Banking on Eight Years of Equipoise
Judith Hochman, L. David Hillis, MD and Richard A. Lange, MD, MBA
(Continued from Part I: Aiming to Beat Bias with Blinding) On August 1, 2011, the Langone Medical Center at New York University announced that the National Heart, Lung, and Blood Institute has provided a grant to fund the ISCHEMIA study of an invasive strategy versus optimal medical management in patients with stable coronary artery disease and […]
August 8th, 2011
Will ISCHEMIA Tell Us More Than COURAGE? Part I: Aiming to Beat Bias with Blinding
Judith Hochman, L. David Hillis, MD and Richard A. Lange, MD, MBA
On August 1, 2011, New York University announced that the National Heart, Lung, and Blood Institute would fund the ISCHEMIA study of an invasive strategy versus optimal medical management in patients with stable coronary artery disease and moderate-to-severe ischemia. We welcome the members of the study Executive Committee, chaired by Dr. Judith Hochman, to answer […]
August 1st, 2011
Going Beyond COURAGE: NHLBI Funds the ISCHEMIA Study
Larry Husten, PHD
The NHLBI has awarded an $84 million grant to fund the International Study of Comparative Health Effectiveness with Medical and Invasive Approaches (ISCHEMIA). The trial will randomize 8,000 patients with stable ischemic heart disease and moderate-to-severe ischemia. Two different treatment strategies will be compared: An invasive strategy, consisting of early routine cardiac catheterization followed by revascularization […]