CardioExchange Archive

June 30th, 2014

Selections from Richard Lehman’s Literature Review: June 30th

Richard Lehman, BM, BCh, MRCGP

This week’s topics include atrial fibrillation and cryptogenic stroke, higher potency statins and the risk for new diabetes, and more.

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June 26th, 2014

To Screen or Not for AF: Is That the Question?

Physician's First Watch, CardioExchange Staff

Up to one third of ischemic strokes are of uncertain etiology or “cryptogenic,” meaning that there is no overt explanation such as severe carotid stenosis, intracranial stenosis, or documented atrial fibrillation (AF). For some of these patients, intermittent AF may be present and could explain the ischemic stroke. This issue has been addressed by two […]

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March 20th, 2013

Controversial PFO Closure Trials Published in NEJM

Larry Husten, PHD

Two controversial trials testing PFO closure in patients with cryptogenic stroke missed their primary endpoints but contained suggestions of possible benefit.

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July 24th, 2012

St. Jude Spills the Beans on PFO Closure Trial

Larry Husten, PHD

Larry Husten asks readers to assess the ethical dimensions of St. Jude’s recent statements about the RESPECT trial.

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May 6th, 2012

Patent Foramen Ovale — Are the Choices Patently Obvious?

Shelby Kutty, MD and John Ryan, MD

Shelby Kutty explains what we know and what we don’t know about how to manage patients with a PFO.

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March 14th, 2012

Achieving CLOSURE: Final Act of PFO Closure Device Trial

Larry Husten, PHD

Nine years after getting underway, results of the CLOSURE 1 trial of PFO closure for cryptogenic stroke are finally published in the New England Journal of Medicine.

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