Posts Tagged ‘chronic thromboembolic pulmonary hypertension’

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July 29th, 2013

Selections from Richard Lehman’s Literature Review: July 29th

This week’s topics include riociguat for chronic thromboembolic pulmonary hypertension, renal outcomes associated with invasive vs. conservative management of ACS, statins and musculoskeletal conditions, arthropathies, and injuries, and more.


July 25th, 2013

Novel Pulmonary Hypertension Drug Shows Modest Promise in Phase 3 Trials

A new drug appears to have promising — but not game-changing — effects in people with two forms of pulmonary hypertension. Riociguat, a soluble guanylate cyclase stimulator under development by Bayer, is thought to have vasodilating, antiproliferative, and antifibrotic effects. Results of two phase 3, placebo-controlled trials were published today in the New England Journal of Medicine. CHEST-1 studied the clinical […]


July 25th, 2013

The Changing Landscape of Pulmonary Hypertension

Two multicenter clinical trials published in the New England Journal of Medicine explore the role of a new oral pulmonary vasodilator in pulmonary hypertension.