November 21st, 2014
Encouraging Results for Two New Drugs for Hyperkalemia
Larry Husten, PHD
Two new agents under development may help curb and prevent hyperkalemia, the common and serious side effect of drugs that inhibit the renin-angiotensin-aldosterone system (RAAS), which are the cornerstones of the treatment of chronic kidney disease and heart failure. In a phase 3 study, published online in the New England Journal of Medicine, researchers first randomized 753 […]
June 30th, 2014
Selections from Richard Lehman’s Literature Review: June 30th
Richard Lehman, BM, BCh, MRCGP
This week’s topics include atrial fibrillation and cryptogenic stroke, higher potency statins and the risk for new diabetes, and more.
March 4th, 2014
AF Patients with Chronic Kidney Disease Also Benefit from Warfarin
Larry Husten, PHD
Anticoagulation is a cornerstone of therapy for atrial fibrillation because it lowers the heightened risk for stroke in this population. People with chronic kidney disease are also at increased risk for stroke, but the benefits of anticoagulation are less clear in this group, and anticoagulation is used less often in AF patients who have CKD. […]
February 3rd, 2014
Selections from Richard Lehman’s Literature Review: February 3rd
Richard Lehman, BM, BCh, MRCGP
This week’s topics include biomarkers for systemic sclerosis, the effectiveness of ICDs for primary prevention of sudden cardiac death, and more.
October 22nd, 2013
No Support for Broad Screening of Chronic Kidney Disease
Larry Husten, PHD
Although taught in medical school and widely used in clinical practice, broad screening of otherwise healthy people for chronic kidney disease (CKD) is unwarranted, according to new recommendations from the American College of Physicians published in the Annals of Internal Medicine. People with early kidney disease, who are classified as having stages 1 to 3 CKD, usually […]
October 21st, 2013
Selections from Richard Lehman’s Literature Review: October 21st
Richard Lehman, BM, BCh, MRCGP
This week’s topics include cholecalciferol to reduce BP in older patients with isolated systolic hypertension, the FREEDOM trial, and more.
August 27th, 2013
Selections from Richard Lehman’s Literature Review: August 27th
Richard Lehman, BM, BCh, MRCGP
This week’s topics include BP and mortality in U.S. veterans with CKD and improved BP control associated with a large-scale hypertension program.
September 6th, 2012
Selections from Richard Lehman’s Literature Review: September 6th
Richard Lehman, BM, BCh, MRCGP
This week’s topics includes studies on aspirin plus clopidogrel in patients with recent lacunar stroke and the risk of coronary events in patients with either CKD or diabetes.
August 28th, 2012
Selections from Richard Lehman’s Literature Review: August 28th
Richard Lehman, BM, BCh, MRCGP
This week’s topics include studies on biolimus-eluting stents vs. bare-metal stents, risk markers to improve CV event prediction, common carotid intima-media thickness and CV risk prediction, aspirin with alteplase for acute ischemic stroke, and lipid-lowering therapy (and its benefits and harms) in patients with CKD.
August 20th, 2012
Selections from Richard Lehman’s Literature Review: August 20th
Richard Lehman, BM, BCh, MRCGP
This week’s topics include studies on the benefits of drug-eluting vs. bare-metal stents, using walking speed and blood pressure measurements to predict mortality in the elderly, stroke and bleeding in AF with chronic kidney disease, and the diagnosis and management of peripheral artery disease.
NEJM Journal Watch — Recent Cardiology Articles- Anticoagulation in Patients with Cancer-Associated Pulmonary Embolism: How Long is Long Enough?
- Spironolactone Use After Percutaneous Intervention for Acute Myocardial Infarction
- CRISPR/Cas9 Gene Editing for Transthyretin Cardiomyopathy
- Does Colchicine Reduce Cardiac Events After Myocardial Infarction?
- First-Line Therapy for Ventricular Tachycardia After MI: What's the Best Approach?