March 20th, 2013
Controversial PFO Closure Trials Published in NEJM
Larry Husten, PHD
Two controversial trials testing PFO closure in patients with cryptogenic stroke missed their primary endpoints but contained suggestions of possible benefit.
October 25th, 2012
TCT: Two PFO Closure Trials Miss Primary Endpoints
Larry Husten, PHD
Two trials presented today at the TCT meeting in Miami testing the benefits of PFO closure in patients with cryptogenic stroke have failed to convincingly demonstrate any significant benefit for the controversial procedure. The RESPECT (Randomized Evaluation of Recurrent Stroke Comparing PFO Closure to Established Current Standard of Care Treatment) trial randomized 980 patients to PFO closure with the […]
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