October 21st, 2010
INR Home Testing Found Comparable to Point-of-Care Testing
Larry Husten, PHD
Weekly INR self-testing at home is comparable to monthly point-of-care testing, according to results of THINRS (the Home International Normalized Ratio Study), published in the New England Journal of Medicine. David Matchar and colleagues found no difference in the incidence of stroke, major bleeding episode, or death in the 2922 patients taking warfarin who were randomized to […]
August 31st, 2010
Apixaban Beats Aspirin for Stroke Prevention in AF
Larry Husten, PHD
The AVERROES (Apixaban Versus Acetylsalicylic Acid (ASA) to Prevent Strokes) trial randomized 5600 AF patients who were unable to take warfarin to receive either aspirin or apixaban, a factor Xa inhibitor. (Another trial still underway, ARISTOTLE, is a direct comparison of warfarin and apixaban in AF.) AVERROES was stopped early after the Data Monitoring Committee […]
NEJM Journal Watch — Recent Cardiology Articles- Modeling the Cost-Effectiveness of a Polypill to Prevent Cardiovascular Disease
- More Data on the Cognitive Safety of Very Low LDL-C Levels
- Is “As-Needed” Blood Pressure Medication Really Needed in Inpatients?
- Major and Intracranial Hemorrhage Risk with Direct Oral Anticoagulants vs. Aspirin
- Chlorthalidone vs. Hydrochlorothiazide for Hypertension: Renal Outcomes