December 10th, 2012
Selections from Richard Lehman’s Literature Review: December 10th
Richard Lehman, BM, BCh, MRCGP
This week’s topics include a comparison of warfarin and new oral anticoagulants for managing AF and VTE, two studies of a monoclonal antibody to PCSK9 in patients with hypercholesterolemia, and more.
December 7th, 2012
Heparin Labels Will Be Revised to Reduce Dosing Miscalculations
Kristin J. Kelley, CardioExchange Staff
Heparin manufacturers will now be required to state the total drug strength of the entire container on their labels, the FDA announced on Thursday. The revisions, proposed by the United States Pharmacopeia (USP) in order to avoid medication errors caused by dosing miscalculations, will take effect on May 1, 2013. The new labels for heparin […]
December 7th, 2012
Should Body Weight Influence Choice of Antihypertensive Therapy?
Larry Husten, PHD
The hypertension field has been troubled by repeated observations that normal weight patients have more cardiovascular (CV) events than obese patients. Now a new analysis of a large hypertension trial confirms this finding but also suggests that it may be explained by either an adverse effect of diuretics or a protective effect of calcium-channel blockers in non-obese […]
December 5th, 2012
Aspirin Resistance May Not Be Real
Larry Husten, PHD
Is it resistance or pseudoresistance? According to a new study published in Circulation, aspirin resistance may be a myth, an artifact of the enteric coating of most aspirin tablets. The coating, which is designed to prevent gastrointestinal side effects caused by aspirin, may delay or conceal the effects of the drug, the study suggests, but the antiplatelet effects will […]
December 3rd, 2012
The Role of Social Media in Fighting Childhood Obesity
Larry Husten, PHD
“More parental involvement and more interaction with counselors and peers was associated with greater success rates for overweight children and teens who participated in an online intervention.”
December 3rd, 2012
Selections from Richard Lehman’s Literature Review: December 3rd
Richard Lehman, BM, BCh, MRCGP
This week’s topics include the association between aldosterone-antagonist therapy and mortality and readmission among patients with HF and reduced EF, warfarin therapy after bioprosthetic AVR, and more.
November 29th, 2012
European Medicines Agency Destroys the Dam: Slight Dampness Results
Richard Lehman, BM, BCh, MRCGP
Richard Lehman recounts an EMA data transparency workshop during which ideas for how to execute its new policy of allowing access to all data submitted for drug licensing were discussed.
November 28th, 2012
The End of Fellowship: What Happens Next?
John Ryan, MD
Our training programs have a uniform deficiency — they do not prepare fellows on how to leave. I know this well, as I am currently transitioning from cardiology fellow to faculty member. Fellows typically enter medical school in their twenties and over the next ten years become institutionalized into full-time understudies. Part of this is […]
November 26th, 2012
Selections from Richard Lehman’s Literature Review: November 26th
Richard Lehman, BM, BCh, MRCGP
This week’s topics include fish oil and postoperative AF, low-dose aspirin for preventing recurrent VTE, a long-term comparison of endovascular and open repair of abdominal aortic aneurysm, and more.
November 19th, 2012
Comprehensive Guidelines for Stable Ischemic Heart Disease Released
Larry Husten, PHD
New comprehensive guidelines for the diagnosis and treatment of stable ischemic heart disease have been released by the ACCF/AHA Task Force on Practice Guidelines.
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