April 8th, 2014
Study Suggests Link Between Viagra and Melanoma
Larry Husten, PHD
In recent years, researchers have uncovered a potentially important pathway whereby PDE5A inhibitors (which include sildenafil — Viagra — and other drugs used to treat erectile dysfunction and pulmonary hypertension) could potentially increase the risk for developing melanoma. Now a study provides early evidence showing an association between sildenafil and melanoma, though, like all observational […]
April 8th, 2014
Some Thoughts on E-Communication and the Future of Medicine
Ahmad M Slim, M.D.
Dr. Ahmad Slim discusses the rise of digital communication between physicians and patients.
April 7th, 2014
Selections from Richard Lehman’s Literature Review: April 7th
Richard Lehman, BM, BCh, MRCGP
This week’s topics include SYMPLICITY HTN-3, CoreValve, MADIT-CRT, and more.
April 7th, 2014
Dabigatran Approved for Treatment of DVT and PE
Larry Husten, PHD
Boehringer Ingelheim announced on Monday that the FDA has approved dabigatran (Pradaxa) for the treatment of venous thromboembolism (VTE), which includes both deep venous thrombosis (DVT) and pulmonary embolism (PE), and to reduce the risk of recurrent DVT and PE in patients who have been previously treated. All three of the new oral anticoagulants — dabigatran, rivaroxaban (Xarelto), […]
April 3rd, 2014
Cardiovascular Disease Declines in Rich Countries but Grows Elsewhere
Larry Husten, PHD
A new Global Cardiovascular Disease (CVD) Atlas portrays a divided world where rich countries are gradually freeing themselves from the yoke of CVD but where many poor and middle-income countries are still struggling. Ischemic heart disease and stroke were the two biggest contributors to the global burden of disease in 2010, accounting for 5.2% and 4.1%, […]
March 31st, 2014
Master of All Trades
Saurav Chatterjee, MD
Saurav Chatterjee reflects on the growing demands of fellows embarking on careers in private practice.
March 31st, 2014
Aspirin and Clonidine Fail to Help Surgery Patients
Larry Husten, PHD
Myocardial infarction (MI) is among the most common and serious side effects of noncardiac surgery. An effective regimen to minimize this risk has been the subject of considerable debate in recent years. The controversy was recently exacerbated because the recommendation to use beta-blockers in this setting was based on research which has now been discredited. Substantial […]
March 30th, 2014
High-Sensitivity Troponin Test Could Identify Low-Risk Chest Pain Patients in the ED
Larry Husten, PHD
Approximately 15-20 million people in Europe and the United States go to the emergency department every year with chest pain. Many can be discharged early if they are not having an acute coronary syndrome. A large, new, single-center observational study, presented at the American College of Cardiology meeting in Washington, DC and published simultaneously in the Journal […]
March 30th, 2014
Taking Patient-Centeredness to the Next Level at ACC.14
Kumar Dharmarajan, MD MBA
A fellow discusses an interesting lecture approach at ACC.14.
March 30th, 2014
Are Digital Conferences the Way of the Future?
Saurav Chatterjee, MD
A fellow reflects on how technology may impact meetings in the years to come.