June 24th, 2014
In Emerging China, STEMI Admissions Skyrocket But Treatment Lags
Larry Husten, PHD
Accompanying all the other changes in China over the past decade, admission to the hospital for ST-segment elevation MI (STEMI) has soared, according to a paper published in the Lancet. Although the study finds that there have been some genuine improvements in treatment, the Chinese healthcare system still has a long way to go to improve […]
June 24th, 2014
FDA Recalls Another Batch of Generic Metoprolol
Larry Husten, PHD
The FDA has recalled more than 13,000 bottles of metoprolol succinate extended-release tablets manufactured by Dr. Reddy’s Laboratories. In addition, the agency recently recalled another lot of generic metoprolol from a different company, Wockhardt. Both recalls were for medicines manufactured at facilities in India. There have been multiple reports in recent years of problems with generic […]
June 23rd, 2014
Unethical Health Screening: When Unnecessary Tests Do More Harm Than Good
Ethan J Weiss, M.D.
Ethan Weiss discusses how unnecessary cardiovascular screening can lead to serious consequences.
June 23rd, 2014
Selections from Richard Lehman’s Literature Review: June 23rd
Richard Lehman, BM, BCh, MRCGP
This week’s topics include thrombolysis for pulmonary embolism, the effect of screening and lifestyle counseling on the incidence of ischemic heart disease in the general population, and more.
June 23rd, 2014
FDA: Risk for Venous Thromboembolism with All Testosterone Products
Kristin J. Kelley, CardioExchange Staff
The FDA is requiring an expanded label change to all approved testosterone products to warn of the increased risk for venous thromboembolism. Labels currently address the risk for clots associated with polycythemia caused by testosterone treatment. The action follows reports of blood clots in testosterone users unrelated to polycythemia. The agency says the warning is not […]
June 23rd, 2014
Mobile Cardiovascular Screening Programs Come Under Fire
Larry Husten, PHD
The consumer group Public Citizen has urged 20 hospitals to sever their involvement in a mobile cardiovascular screening program. The HealthFair Cardiovascular Screening Packages are unethical, mislead consumers, and do more harm than good, according to Public Citizen. In a statement, the president of the American College of Cardiology, Patrick O’Gara, said that “the questions raised […]
June 23rd, 2014
If You Snus, You Lose: Study Shows Benefits of Quitting Smokeless Tobacco
Larry Husten, PHD
The adverse effects of smoking are well known and documented. The effect of smokeless tobacco is less clear. Now a study from Sweden, published in Circulation, offers evidence that quitting smokeless tobacco after MI is about as beneficial as quitting smoking. The results do not support the common view that smokeless tobacco is a safe alternative […]
June 19th, 2014
Genetic Studies May Help Unravel the Triglyceride Problem
Larry Husten, PHD
The precise role of triglycerides in heart disease has been very difficult to determine. To help untangle the knotty problem two research groups studied large populations and identified rare variations in a gene (APOC3) that encodes for apolipoprotein C3, which is known to increase triglyceride levels. In the first paper, published in the New England Journal […]
June 18th, 2014
Yet Another Delay for Boston Scientific’s Watchman Device
Larry Husten, PHD
Boston Scientific hopes the third time will be the charm. The company disclosed on Tuesday yet another obstacle in the path to approval for its novel Watchman left atrial appendage closure device for the prevention of stroke in patients with atrial fibrillation. Although it has already been before two FDA advisory panels, the company said […]
June 17th, 2014
Mixed Results for Thrombolysis in Pulmonary Embolism
Larry Husten, PHD
The role of thrombolytic therapy for the treatment of pulmonary embolism has been unclear, as it has been difficult to measure the precise balance between enhanced clot-dissolving efficacy and greater bleeding risk produced by thrombolysis when compared with conventional anticoagulation. A new meta-analysis published in JAMA analyzed data from 16 randomized trials including 2115 patients. Overall, […]