Amy Herman

All posts by Amy Herman

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November 2nd, 2010

Meta-Analysis Provides Little Support for Prophylactic ICD Use in Older Adults

Prophylactic implantable cardioverter-defibrillator (ICD) therapy does not appear to significantly improve survival among older adults with severe left ventricular dysfunction, according to a meta-analysis in the Annals of Internal Medicine. Researchers analyzed data from five randomized trials comparing ICD therapy with medical treatment among some 5800 adults with cardiomyopathy. Older adults (defined as 60 and older […]


November 2nd, 2010

Is Dabigatran More Cost-Effective Than Warfarin in AF?

Dabigatran, newly approved by the FDA to prevent stroke in patients with atrial fibrillation (AF), might turn out to be a cost-effective alternative to warfarin, according to an Annals of Internal Medicine study. Using data from the RE-LY trial, James Freeman and colleagues modeled the quality-adjusted survival and cost-effectiveness of dabigatran compared with high- or low-dose warfarin […]