November 21st, 2012
What’s The Best Treatment For Abdominal Aortic Aneurysm?
Larry Husten, PHD
Endovascular repair of AAA (abdominal aortic aneurysm) gained enthusiastic acceptance after initial results from three trials (EVAR 1, DREAM, and OVER) found an early survival advantage for endovascular repair compared to open repair. Some of the enthusiasm waned, however, after long-term results from the first two trials found no difference in survival between the groups […]
November 20th, 2012
PFO Occluder Devices Don’t Get No RESPECT
L. David Hillis, MD
David Hillis invokes Rodney Dangerfield in considering the findings of a recent trial of a PFO closure device.
November 19th, 2012
Comprehensive Guidelines for Stable Ischemic Heart Disease Released
Larry Husten, PHD
New comprehensive guidelines for the diagnosis and treatment of stable ischemic heart disease have been released by the ACCF/AHA Task Force on Practice Guidelines.
November 19th, 2012
Selections from Richard Lehman’s Literature Review: November 19th
Richard Lehman, BM, BCh, MRCGP
This week’s topics include multivitamins and cancer prevention in men, a comparison of atorvastatin with or without a PCSK9 Antibody in primary hypercholesterolemia, type-2 diabetes screening and population mortality over 10 years, and more.
November 15th, 2012
FDA Approves Zilver PTX Drug-Eluting Stent for Peripheral Arterial Disease
Larry Husten, PHD
The FDA today approved Cook Medical’s Zilver PTX stent. It is the first drug-eluting stent (DES) approved for the treatment of peripheral arterial disease (PAD) in the superficial femoral and proximal (i.e., above the knee) popliteal artery. The new stent will provide a new treatment option for patients with PAD. Current treatments include exercise, drug […]
November 15th, 2012
In Acute VTE, Novel Oral Anticoagulants and Conventional Therapy Show Similar Efficacy
Nicholas Downing, MD
Novel oral anticoagulants and vitamin K antagonists offer similar protection against venous thromboembolism recurrence, according to a BMJ meta-analysis. However, one of the newer agents, rivaroxaban, seems to offer better protection against bleeding. The analysis included nine randomized controlled trials comparing apixaban, dabigatran, rivaroxaban, or ximelagatran (no longer on the market) with traditional vitamin K […]
November 15th, 2012
Mysterious Disappearing Paper Finally Crops Up in Journal
Larry Husten, PHD
An article about the potential cardiovascular benefits of transcendental meditation takes a circuitous route to publication.
November 13th, 2012
Expert Consensus Document Offers Advice on Troponin Tests
Larry Husten, PHD
A newly published document provides practical advice on the use of the popular and potent troponin tests. The Expert Consensus Document on Practical Clinical Considerations in the Interpretation of Troponin Elevations was developed by the American College of Cardiology Foundation in collaboration with several other societies to help address the many complex issues raised by the introduction […]
November 12th, 2012
Nonfasting Lipid Testing Gains Growing Acceptance
Larry Husten, PHD
Although fasting before a lipid test has long been recommended, a new study and accompanying commentaries make the case that nonfasting lipid levels are acceptable and may even be superior to fasting levels for the assessment of cardiovascular risk. Investigators at the University of Calgary analyzed data from laboratory tests obtained from more than 200,000 […]
November 12th, 2012
Selections from Richard Lehman’s Literature Review: November 12th
Richard Lehman, BM, BCh, MRCGP
This week’s topics include multivitamins for the prevention of CVD in men, the TRILOGY ACS trial, statin use and reduced cancer mortality, and more.