CardioExchange Archive

January 28th, 2014

Problems Persist Despite Gains in Oral Anticoagulant Use

Larry Husten, PHD

Although significant progress has been made in recent years, a new survey from the European Society of Cardiology finds that there are still too many atrial fibrillation patients who are not taking the best medications to reduce their elevated risk for stroke. Many elderly patients are not receiving oral anticoagulants — either traditional warfarin or […]

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October 21st, 2013

Refining the Optimal Duration of Dual Antiplatelet Therapy After DES Implantation

Cheol-Whan Lee, MD and Seung-Jung Park, MD.,Ph.D

Cheol Whan Lee and Seung-Jung Park discuss their study group’s randomized trial comparing dual antiplatelet therapy with aspirin alone beyond 12 months after drug-eluting stent implantation.

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September 12th, 2013

Aspirin Therapy with Anticoagulation in Patients with Afib?

Benjamin A. Steinberg, MD and John Ryan, MD

An interview with Benjamin Steinberg about an analysis of data from the ORBIT-AF registry, in which patients with atrial fibrillation who were taking oral anticoagulation and aspirin had a higher risk of bleeding than patients on anticoagulation only.

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July 8th, 2013

Selections from Richard Lehman’s Literature Review: July 8th

Richard Lehman, BM, BCh, MRCGP

This week’s topics include a home-based walking intervention for those with PAD, BNP screening and collaborative care for HF, clopidogrel with aspirin in acute minor stroke or transient ischemic attack, and more.

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June 26th, 2013

Some Patients with Minor Stroke or TIA May Benefit from Early Clopidogrel and Aspirin

Larry Husten, PHD

Some people with minor ischemic stroke or transient ischemic attack (TIA) may benefit from dual antiplatelet therapy with aspirin and clopidogrel, according to a large new study from China published in the New England Journal of Medicine. In the immediate period following a TIA or minor stroke, people are at high risk for having a major stroke. Aspirin […]

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June 10th, 2013

Selections from Richard Lehman’s Literature Review: June 10th

Richard Lehman, BM, BCh, MRCGP

This week’s topics include controlling diabetes through surgery or medical management, the risk for diabetes among those taking statins, and aspirin vs. low-molecular-weight heparin for extended VTE prophlyaxis after total hip replacement.

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April 2nd, 2013

Selections from Richard Lehman’s Literature Review: April 2nd

Richard Lehman, BM, BCh, MRCGP

This week’s topics include the TACT study of chelation therapy, off-pump vs. on-pump CABG, clopidogrel with or without aspirin in those taking oral anticoagulants and undergoing PCI, and more.

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December 5th, 2012

Aspirin Resistance May Not Be Real

Larry Husten, PHD

Is it resistance or pseudoresistance? According to a new study published in Circulation, aspirin resistance may be a myth, an artifact of the enteric coating of most aspirin tablets. The coating, which is designed to prevent gastrointestinal side effects caused by aspirin, may delay or conceal the effects of the drug, the study suggests, but the antiplatelet effects will […]

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November 26th, 2012

Selections from Richard Lehman’s Literature Review: November 26th

Richard Lehman, BM, BCh, MRCGP

This week’s topics include fish oil and postoperative AF, low-dose aspirin for preventing recurrent VTE, a long-term comparison of endovascular and open repair of abdominal aortic aneurysm, and more.

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November 4th, 2012

Platelet-Function Testing in Coronary Stenting: Frozen in Its Tracks

Gilles Montalescot, MD, PhD

An ARCTIC trial investigator discusses possible reasons why antiplatelet-drug and dosing adjustments, guided by platelet-function testing, did not improve clinical outcomes for stented patients.

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