CardioExchange Archive

July 17th, 2014

Clinical Events vs. Quality of Life: An Insider’s View of TACT

Gervasio Antonio Lamas, MD

TACT investigator Gervasio Lamas provides perspective on two new TACT papers that appear to have contradictory results.

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November 19th, 2013

An Insider’s Look at TACT

Gervasio Antonio Lamas, MD

TACT investigator Gervasio Lamas provides an inside look at how the TACT trial began, the controversial journey so far, and what he hopes it will accomplish.

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November 19th, 2013

TACT Substudy Suggests Possible Strong Benefit for Chelation in Diabetics

Larry Husten, PHD

One year ago the results of the TACT trial were published in JAMA, sparking an enormous controversy over the propriety of publishing a trial suggesting that chelation therapy might be beneficial in people with cardiovascular disease. Chelation therapy has long been a staple of alternative medicine, but until the publication of TACT it had received […]

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April 9th, 2013

The TACT Investigators Respond to Questions

Gervasio Antonio Lamas, MD, Daniel Mark, Christine Goertz, DC, PhD, Robin Boineau, M.D., M.A., Kerry L. Lee, Ph.D. and Harlan M. Krumholz, MD, SM

The publication in JAMA of the NIH’s Trial to Assess Chelation Therapy (TACT) has reignited a heated debate about the trial. The TACT investigators have generously agreed to respond to questions posed by Harlan Krumholz.

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April 2nd, 2013

Perspective On The Controversy About The TACT Trial

Sanjay Kaul, MD

The NIH TACT trial of chelation therapy has been the subject of intense criticism. In my opinion, the arguments that the TACT results are dubious or not valid are overstated. While the debate surrounding TACT is clearly warranted and welcome, I hope it generates more light than heat.

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