June 18th, 2013
Statin Toxicity Associated with CYP3A4-Inhibiting Antibiotics
Higher rates of hospitalization for rhabdomyolysis occur among patients on statins who also start taking clarithromycin or erythromycin, which inhibit statin metabolism, according to an Annals of Internal Medicine study. Using provincial databases, researchers examined 30-day outcomes among some 140,000 Ontario residents who were taking a statin metabolized by the cytochrome P450 isoenzyme 3A4 (CYP3A4). All […]
NEJM Journal Watch — Recent Cardiology Articles- To Lower Stroke Risk in Patients Undergoing Atrial Fibrillation Ablation, Is a Device or a Medication Better?
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