November 21st, 2014
Encouraging Results for Two New Drugs for Hyperkalemia
Larry Husten, PHD
Two new agents under development may help curb and prevent hyperkalemia, the common and serious side effect of drugs that inhibit the renin-angiotensin-aldosterone system (RAAS), which are the cornerstones of the treatment of chronic kidney disease and heart failure. In a phase 3 study, published online in the New England Journal of Medicine, researchers first randomized 753 […]
November 21st, 2014
Encouraging Results For Two New Drugs For Hyperkalemia
Larry Husten, PHD
Two new agents under development may help curb and prevent hyperkalemia, the common and serious side effect of drugs that inhibit the renin-angiotensin-aldosterone system (RAAS), which are the cornerstones of the treatment of chronic kidney disease and heart failure. … Click here to read the full post on Forbes.
April 16th, 2013
Selections from Richard Lehman’s Literature Review: April 16th
Richard Lehman, BM, BCh, MRCGP
This week’s topics include fibrinolysis or primary PCI in STEMI, the effect of lower sodium intake on health, and the effect of increased potassium intake on CV risk factors and disease.
May 14th, 2012
Selections from Richard Lehman’s Literature Review: Week of May 14th
Richard Lehman, BM, BCh, MRCGP
This week Richard discusses studies of glucose, insulin, and potassium for MI, elective PCI with and without surgical standby, and varenicline and CV risk.
January 10th, 2012
Researchers Find Lower Sweet Spot for Potassium Levels in MI
Larry Husten, PHD
Current guidelines for the treatment of acute MI recommend that serum potassium be maintained between 4.0 and 5.0 mEq/L, and some believe that the upper limit could be raised to 5.5, but evidence is based on small, outdated studies. Now a study published in JAMA suggests that the ideal potassium range should be adjusted downward. Abhinav Goyal and […]
July 12th, 2011
Study Finds High Sodium-Potassium Ratio Strongly Tied to Mortality and CV Disease
Larry Husten, PHD
The separate roles of sodium and potassium in cardiovascular disease have been extensively observed in epidemiologic studies. Now a study published in the Archives of Internal Medicine examines their joint effect. Quanhe Yang and colleagues analyzed data from 12,267 adults participating in the Third National Health and Nutrition Examination Survey. As expected, they found that higher […]