May 27th, 2014
Choosing a Prosthetic Valve: What Do You Say to Your Patient?
Harlan M. Krumholz, MD, SM
In this scenario based on prosthetic valve choice, Harlan Krumholz asks, “What do you say to your patient?”
December 19th, 2012
Pradaxa To Be Contraindicated in Patients with Mechanical Heart Valves
Larry Husten, PHD
Boehringer Ingelheim is starting to inform physicians about a new contraindication for its oral anticoagulant drug Pradaxa (dabigatran). The company has told investigators in trials utilizing dabigatran that it will shortly be sending a “Dear Doctor Letter,” also known as a Direct Healthcare Professional Communication (DHPC), to healthcare professionals. The letter will inform physicians that, […]
October 23rd, 2012
Setback for Trial Studying Dabigatran After Mechanical Valve Surgery
Larry Husten, PHD
Despite the recent advent of novel oral anticoagulants, the much-maligned warfarin remains the only current option available for patients who have received a mechanical valve. Now the first trial to explore this indication for a newer oral anticoagulant has suffered a setback. Last year, Boehringer Ingelheim announced the launch of the RE-ALIGN trial, a phase 2, […]
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