January 28th, 2013
Study Warns Against Dual Blockade of Renin-Angiotensin System in Heart Failure and Hypertension
Larry Husten, PHD
The enormous success of ACE inhibitors in hypertension and heart failure spurred hope that adding a second drug to block the renin-angiotensin system would yield improved outcomes. Although definitive evidence supporting dual blockade of the renin-angiotensin system has never been found, more than 200,000 patients in the U.S. currently receive this therapy. Now a large new meta-analysis […]
August 28th, 2012
WOEST: Get Rid of the Aspirin in Triple Therapy
Larry Husten, PHD
According to current guidelines and clinical practice, PCI patients already taking an oral anticoagulant generally end up on triple therapy comprising the anticoagulant plus clopidogrel and aspirin. However, there is no supporting evidence base for this approach, and the triple-therapy regimen is known to increase bleeding complications. Now a new study — the first randomized […]
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