CardioExchange Archive

November 4th, 2012

FREEDOM Lends Strong Support to CABG for Diabetics with Multivessel Disease

Larry Husten, PHD

CABG is associated with better cardiovascular outcomes than PCI in patients with diabetes and multivessel disease.

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October 4th, 2012

U.K. Study Casts Doubts on Value of Type 2 Diabetes Screening

Larry Husten, PHD

The dramatic growth in type 2 diabetes has resulted in increased interest in screening programs. Now a new study published in the Lancet raises concerns that screening programs may not result in long-term improvement in outcomes. In the ADDITION-Cambridge study, investigators in the U.K. randomized general practices to either screening or no screening.  The practices allocated to screening were […]

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October 1st, 2012

Selections from Richard Lehman’s Literature Review: October 1st

Richard Lehman, BM, BCh, MRCGP

This week’s topics include exercise and mortality in those with diabetes, BP targets in those with type-2 diabetes, and the diagnostic accuracy of FFR from CT angiography.

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September 13th, 2012

A Manhattan Project to End the Obesity Epidemic

Larry Husten, PHD

A newly launched nonprofit organization, the Nutrition Science Initiative, will try to find an answer to the question,  “What should we eat to be healthy?” Called NuSI (pronounced “new see”) for short, the organization is nothing if not ambitious: its goal is to seek “the end of fad diets and high obesity rates.” NuSI’s founders are Gary Taubes and Peter Attia. Taubes is the […]

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September 6th, 2012

Selections from Richard Lehman’s Literature Review: September 6th

Richard Lehman, BM, BCh, MRCGP

This week’s topics includes studies on aspirin plus clopidogrel in patients with recent lacunar stroke and the risk of coronary events in patients with either CKD or diabetes.

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August 21st, 2012

Shining a Light on Standards at Medical Journals

Druin Burch, BM BCh MA MSc, John Stephen Yudkin, MB BChir MD FRCP and Marion Marjorie Mafham, MBChB MD

Recent articles in the diabetes literature might provide more evidence about editorial standards than about glycemic control.

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August 9th, 2012

Reports from JUPITER and Taiwan: Benefits of Statins Outweigh Risk for Diabetes

Larry Husten, PHD

Two new papers provide further evidence that statin use is associated with an increased risk for diabetes, but both studies also find that the benefits of statins still outweigh the risks. In one report, published in the Lancet, Paul Ridker and colleagues analyze data from the JUPITER trial, which compared rosuvastatin to placebo in a primary-prevention population. Among the 17,603 […]

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July 12th, 2012

Selections from Richard Lehman’s Literature Review: July 12th

Richard Lehman, BM, BCh, MRCGP

This week’s topics include sex differences in the protective effect of statins, an action measure to lower BP among diabetics, a prediction tool for initial survivors of in-hospital cardiac arrest, the diagnosis and treatment of pulmonary embolism, an intervention to prevent medication errors after hospital discharge, and rehospitalization after acute MI.

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July 9th, 2012

AHA and ADA Cautiously Endorse Non-Nutritive Sweeteners

Larry Husten, PHD

In a newly released scientific statement, the American Heart Association and the American Diabetes Association offer a cautious endorsement of the use of non-nutritive sweeteners in the diet. But the statement notes that the products are not “magic bullets” and that there is no strong evidence demonstrating their beneficial effects. Sugar in the diet has been linked […]

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June 29th, 2012

Linagliptin and Glimepiride Compared in Type 2 Diabetes

Larry Husten, PHD

Sulfonylureas are often added to metformin to improve glycemic control, but at the known risk of increasing hypoglycemia and weight gain. In a report published in the Lancet, more than 1,500 patients with type 2 diabetes taking metformin were randomized to the addition of either linagliptin, a dipeptidyl peptidase-4 inhibitor, or glimepiride, a sulfonylurea. After two years, the trial […]

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