CardioExchange Archive

November 6th, 2009

Darbepoetin–Trick or Treat? Part II

philipmarsden and Andrew M. Kates, MD

(SEE PART 1 OF SERIES) I was amazed by three things when the results from Trial to Reduce Cardiovascular Events with Aranesp Therapy (TREAT) were presented Friday October 30th, 2009 at the American Society of Nephrology Annual Meeting in San Diego: Thousands of atttendees came to hear TREAT presented by Dr M. Pfeffer–The room was tense […]

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November 2nd, 2009

Genetic Testing in Unexplained Thrombosis – Part I

Harlan M. Krumholz, MD, SM

The case. (For an expert’s response, see Part II) A very healthy 44-year-old man who engaged in daily vigorous physical activity suddenly developed shortness of breath and pleuritic chest pain. He was quickly diagnosed with multiple pulmonary emboli. He was not overweight and had no recent history of long trips, injuries, periods of bed rest, […]

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October 30th, 2009

Being “Safe” Still Isn’t Cool

Joseph S. Ross, MD, MHS

If we are to detect harms early and protect the public’s health while ensuring the availability of effective new therapies, systematic reporting of safety outcomes from all clinical trials must be available.  In the current Archives of Internal Medicine, Isabelle Pitrou and colleagues (FREE) review the reporting of safety data in randomized, controlled trials published during […]

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October 30th, 2009

The Obese Passenger: Confronting the Obesity Epidemic Personally and Professionally

Juan J. Rivera, MD, MHS

I am a creature of routine and order, and therefore don’t do very well with Southwest Airlines’ lack of seat assignment. Not so long ago, during a business trip to San Antonio, I was looking at my group C boarding pass and wondering if there would be any room for my carry-on luggage, or if […]

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October 30th, 2009

Is the Framingham Risk Score Over the Hill?

JoAnne M. Foody, MD

The Framingham study has revolutionized our understanding of cardiovascular disease, but I wonder: is the 60-year-old study’s risk score getting a little long in the tooth? Faced with the epidemic of heart disease and growing numbers of younger people worried about heart disease risk, I find that Framingham provides me little guidance. As I see it, Framingham […]

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