CardioExchange Archive

February 12th, 2013

ACC and STS Break New Ground to Test TAVR for Unapproved Uses

Larry Husten, PHD

In a startling break with tradition, the American College of Cardiology (ACC) and the Society of Thoracic Surgeons (STS) will manage and run their own clinical trials testing expanded uses for transcatheter aortic valve replacement (TAVR). The two medical groups have recently been granted an investigational device exemption (IDE) by the FDA for one such […]

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February 12th, 2013

Conflict Of Interest Is A Complex Issue

Robert McKinnon Califf, MD and Harlan M. Krumholz, MD, SM

In a recent editorial in the Journal of the American College of Cardiology, Robert Califf discusses a few of the many complex questions related to the conflict of interest issue. Here CardioExchange’s Harlan Krumholz further explores the issue with Califf. CardioExchange: Do you think that conflict of interest issues are mostly an issue about optics and […]

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February 11th, 2013

Selections from Richard Lehman’s Literature Review: February 11th

Richard Lehman, BM, BCh, MRCGP

This week’s topics include the effect of ramipril on walking times and quality of life among those with PAD and intermittent claudication, genetic associations with valvular calcification and aortic stenosis, and more.

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February 11th, 2013

FDA Wants Cardiovascular Safety Data Before Approving Insulin Degludec

Larry Husten, PHD

The FDA informed Novo Nordisk on Friday that it would not approve the company’s highly anticipated long-acting insulin degludec products (Tresiba and Ryzodeg) until it receives data from a cardiovascular outcomes trial. Approval of the drugs had been widely anticipated for this year, following a positive recommendation from an FDA advisory committee last fall. But the committee […]

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February 9th, 2013

A Cardiologist Tests an Activity Tracker

Shengshou Hu, M.D.

Looking to lose a few pounds, Wes Fisher tries out a new physical activity tracking device and shares his experience.

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February 6th, 2013

Genetic Study Identifies Strong Links to Aortic Valve Disease

Larry Husten, PHD

A genetic component is believed to play an important role in valvular heart disease, but the specific genes involved have not been identified. Now an interntional group of researchers has identified genetic variations that increase the risk for valvular calcification. In an article published in the New England Journal of Medicine, members of the Cohorts for Heart and […]

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February 5th, 2013

Back To The Future: Resurrected Data From 1960s Trial Might Impact Contemporary Dietary Fat Debate

Larry Husten, PHD

In an exceedingly strange turn of events, data from a clinical trial dating from the 1960s, long thought to be lost, has now been resurrected and may contribute important new information to the very contemporary controversy over recommendations about dietary fat composition. The American Heart Association has long urged people to increase their consumption of […]

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February 5th, 2013

The Sun Is About to Shine

Joseph S. Ross, MD, MHS

Will the Physician Payment Sunshine Act help to prevent conflict of interest or will it limit good science?

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February 4th, 2013

Selections from Richard Lehman’s Literature Review: February 4th

Richard Lehman, BM, BCh, MRCGP

This week’s topics include blood transfusion and increased mortality in MI, proteotoxicity and cardiac dysfunction in the elderly, combined fitness and statin treatment on mortality in veterans with dyslipidemia, and more.

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February 1st, 2013

Reflections on Our Profession: Dr. James Fang Named Chief of Cardiology at the University of Utah

James Fang, MD and John Ryan, MD

Jim Fang reflects on the changing landscape of academic cardiology and the evolving role of the physician investigator.

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