May 15th, 2015
Good Night, and Good Luck
CardioExchange Editors, Staff
A final farewell from the CardioExchange editors
May 13th, 2015
Get a Grip: Global Study Finds Grip Strength Is a Simple and Powerful Predictor Of Death
Larry Husten, PHD
A large global study finds that grip strength is a simple, powerful, and broadly applicable test that can help predict the risk of death and cardiovascular disease. The new findings from the Prospective Urban-Rural Epidemiology (PURE) study were based on data from nearly 140,000 adults in 17 countries. The study participants had their grip strength […]
May 12th, 2015
Diet Drug Study Crashes and Burns in the Wake of Leaked Results
Larry Husten, PHD
The ill-fated Light trial, which was supposed to examine the cardiovascular outcomes of the weight loss drug Contrave, a combination of naltrexone and bupropion marketed by Orexigen and Takeda, came to a spectacular halt today. The action was probably inevitable given the extreme controversy generated earlier this year when it became known that Orexigen had widely disseminated results from an early […]
May 11th, 2015
Selections from Richard Lehman’s Literature Review: May 11th
Richard Lehman, BM, BCh, MRCGP
This week’s topics include a comparison of catheter ablation for persistent AF, left atrial appendage exclusion with the Lariat device, the obesity paradox in type 2 diabetes, and more.
May 11th, 2015
Prominent Harvard Cardiologist Moves to Google X to Head Large Study
Larry Husten, PHD
Here’s a clear sign of the ascending role of digital/precision/personalized medicine: a prominent cardiologist has left a top academic and clinical position in Boston to run a large, innovative study in Silicon Valley. Jessica Mega was widely perceived as a rising star at Harvard Medical School and the Brigham and Women’s Hospital. She has now joined Google X, Google’s research arm, […]
May 7th, 2015
Big Data, Big Problems
John Ryan, MD
Calling attention to the health data generated by today’s wearable devices, John Ryan wonders: Who ultimately owns this information and what can they do with it?
May 7th, 2015
Selections from Richard Lehman’s Literature Review: May 7th
Richard Lehman, BM, BCh, MRCGP
This week’s topics are a comparison of a retrievable inferior vena cava filter plus anticoagulation vs. anticogulation alone for recurrent PE, the cost effectiveness and population impact of statins for primary prevention in U.S. adults age 75 and older, and more.
May 7th, 2015
Advocates Say Precision Medicine Could Lead to Enormous Benefits
Larry Husten, PHD
Personalized and precision medicine (PPM) could deliver hundreds of billions of dollars worth of improved health in the next 50 years in the United States, writes Victor Dzau, the new president of the Institute of Medicine, and coauthors in a Viewpoint published in the Lancet. The authors used a health simulation model to estimate the effect of […]
May 1st, 2015
A Message from the Editor-in-Chief
Harlan M. Krumholz, MD, SM
Harlan Krumholz reflects on the CardioExchange community.
May 1st, 2015
A Message from NEJM Group
Jonathan N. Adler, MD, MS
An important notification about CardioExchange
NEJM Journal Watch — Recent Cardiology Articles- Sex-Based Disparity in CABG Outcomes: Are We Moving Toward Parity?
- Can Genetic and Social Risk Scores Improve Cardiac Risk Prediction?
- Extensive Ablation vs. Pulmonary Vein Isolation in Persistent Atrial Fibrillation
- Can a Novel Stent Design Improve Long-Term Outcomes of Percutaneous Coronary Intervention?
- Are Angiographically-Derived Coronary Physiology Measurements Ready for Use in the Cath Lab?